摘要
Abstract
Objective To explore the effect of the guglielmi detachable coil (GDC) in the embolization of intracranial aneurysms.Methods A total of 60 intracranial aneurysm cases confirmed by cerebral angiography from January 2010 to March 2015 were analyzed retrospectively.All patients were found single focus of tumor.They were divided into two groups according to surgical procedure:The treatment group (n =30) were performed the intracranial aneurysm embolization with GDC,and the control group (n =30) were carried out craniotomy and aneurysmal clipping.The surgical treatment results,complication incidence and prognosis (ADL score) were compared between two groups.Results In the treatment group,there were complete embolization in 22 cases (73.3％),embolization more than 90％ in 5 cases (16.7％) and less than 90％ in 3cases(10.0％).22 cases were achieved dense embolization with stable coils,and 8 cases were achieved partial embolization with stable coils in 7 and diminution in 1.The hospital stays was shorter in treatment group than in control group ((16.1 ± 3.1) vs.(23.9 ± 4.3),P ＜ 0.05)),but no statistical difference in both cost of operation and hospitalization (P ＞ 0.05).There was statistical difference in mortality between the treatment group and control group(0 vs.13.3％,x2 =4.29,P =0.04).The patients with ADL grade Ⅰ and Ⅱ were 25 cases(83.3％) in the treatment group,and was higher than 14 cases (53.8％) in the control group (x2 =5.73,P =0.02).The post-operative complication was found in 4 cases of treatment group including cerebral infarction,hydrocephalus,hemiplegia and pulmonary infection in 1 case respectively,and in 11 cases of control group including 3 of cerebral infarction,2 of hydrocephalus,2 of hemiplegia,3 of pulmonary infection and 1 of gastrointestinal hemorrhage.There was statistical difference in the incidence of complication between two groups (x2 =4.69,P =0.03).Conclusion The treatment of intracranial aneurysm embolization with GDC is effective and safe,and is worthy of further application.关键词
颅内动脉瘤/栓塞,治疗性/电解可脱弹簧圈Key words
intracranial aneurysm/embolization, therapeutic/guglielmi detachable coil (GDC)分类
医药卫生
