中国医学前沿杂志（电子版）2016，Vol.8Issue(6)：160-164,5.
肝癌切除术联合术后 TACE 对肝癌合并门静脉癌栓患者的治疗效果及预后影响因素分析
Analysis of the clinical effect and prognostic factors of postoperative TACE combined with hepatic carcinectomy in the treatment of primary carcinoma of the liver with portal vein tumor thrombus
黄书明 1陈圣开 1张涛1
作者信息
- 1. 重庆市第三人民医院 肝胆外科，重庆 400014
- 折叠
摘要
Abstract
Objective To explore the clinical effect of postoperative TACE combined with hepatic carcinectomy in the treatment of primary carcinoma of the liver with portal vein tumor thrombus and to analyze its prognostic factors. Method From April 2008 to April 2011, 123 primary carcinoma of the liver with portal vein tumor thrombus patients admitted in our hospital were divided into combination group and control group according to the different cancer therapeutics. Patients in combination group were treated with hepatic carcinectomy with postoperative TACE while patients in control group accepted hepatic carcinectomy only. Compared the short-term efficacy for 3 months and the postoperative survival rate of the two groups. Analyzed the prognostic factors by single factor analysis and multiple Logistic regression analysis. Result The total control rate of 3 months after operation, the 1-, 2- and 3-year survival rates of combination group were higher than control group (P < 0.05). Single factor analysis showed that hepatic vein tumor thrombus, tumor thrombus type, number of tumor, diameters of tumor and postoperative TACE were prognostic factors (P < 0.05). And the multiple Logistic regression analysis showed that hepatic vein tumor thrombus, tumor thrombus type and postoperative TACE were independent prognostic factors (P < 0.05). Conclusion In the treatement of primary carcinoma of the liver with portal vein tumor thrombus, hepatic carcinectomy combined with postoperative TACE should be applied as soon as possible to prolonging survival period of patients. Hepatic vein tumor thrombus, tumor thrombus type are the independent prognostic factors of hepatocellular carcinoma with portal vein tumor thrombus.关键词
原发性肝癌/门静脉癌栓/经动脉化疗栓塞/肝癌切除术Key words
Primary carcinoma of the liver/Portal vein tumor thrombus/Transcatheter arterial chemoemb-olization/Hepatic carcinectomy引用本文复制引用
黄书明,陈圣开,张涛..肝癌切除术联合术后 TACE 对肝癌合并门静脉癌栓患者的治疗效果及预后影响因素分析[J].中国医学前沿杂志（电子版）,2016,8(6):160-164,5.
