摘要
Abstract
Objective To investigate the effects of citric acid combined with hypochlorous acid in hemodialysis machine. Methods 10 sets of Fresenius 4008S hemodialysis machine from May 2015 to December 2015 were selected and randomly divided into the observa-tion group and control group, 5 in each group. The control group used citric acid chemical disinfection method, and the observation group used citric acid chemical disinfection combined with hypochlorous acid chemical disinfection. Both groups were taken 100 mL re-verse osmosis water respectively for bacterial culture and endotoxin detection, and the contrast analysis, comprehensive evaluation of the disinfection effect of hemodialysis machine were carried out. The event of failure during using hemodialysis machine in the two groups were recorded. Results Before the disinfection, the bacterial colonies of two groups were ﹥ 100 cfu / mL. After disinfection, the bacterial colonies of the observation group was(12. 36 ± 16. 87) cfu / mL, which was significantly lower than(33. 88 ± 19. 69) cfu / mL of the control group( P ﹤ 0. 05) . The qualified rate of bacterial colonies and qualified rate of endotoxin determination of the observation group were significantly higher than the control group( P ﹤ 0. 05) . Before disinfection, the bacterial endotoxin levels in the hemodialysis machine of the two groups were far beyond the eligibility criteria; after disinfection, the endotoxin levels in the two groups reached the eligible cri-teria, and the endotoxin content detected in the observation group was significantly lower than the control group, the qualified rate of endotoxin higher than the control group with significant differences( P ﹤ 0. 05) . During the use of hemodialysis machine, the average failure rate was 4. 00% in the observation group, which was significantly lower than 20. 00% of the control group ( P ﹤ 0. 05 ) . Conclusion Citric acid combined with hypochlorous acid has a better disinfection efficacy on hemodialysis machine, it can also reduce the machine failure caused by an incomplete sterilization, ensure the normal operation of the machine, and there is a safety guarantee for the treatment of patients.关键词
柠檬酸/次氯酸/血液透析机/消毒作用Key words
citric acid/hypochlorous acid/hemodialysis machine/disinfection effect分类
医药卫生
