摘要
Abstract
Objective To study the effect of isoflurane anesthesia on blood glucose, blood lipid and renal function in patients with cran-iocerebral traum. Methods 90 cases with craniocerebral trauma operation were selected from July 2014 to July 2015 and divided into study group and control group according to the random number table method. The control group was given propofol and fentanyl anes-thesia, the study group received isoflurane anesthesia. The blood glucose and triglyceride preoperative, intraoperative 1, 3, and 2 h of the two groups were compared, and urine volume, serum creatinine, urea nitrogen and uric acid preoperative, postoperative 1, 3 and 7 d after surgery of two groups were compared. Results The blood glucose of intraoperative 3 h reached the peak and then decreased in the study group, the blood glucose of postoperative 2 h reached the peak in the control group, the difference was statistically significant( P ﹤0. 05 ) ; triglyceride was more stable in the study group, intraoperative triglyceride 1 h and 3 h in the control group were significantly elevated, the difference was statistically significant( P ﹤ 0. 05); the urine volume of the first day in the two groups began to increase after operation, and the urine volume was decreased after the seventh day, there was no statistical significance between the two groups ( P ﹥ 0. 05); blood creatinine and urea nitrogen increased on the first day after operation in the two groups, the difference was statisti-cally significant compared preoperative( P ﹤ 0. 05), the difference between the two groups was statistically significant( P ﹤ 0. 05); blood creatinine and urea nitrogen were decreased after the seventh day of operation, there was no significant difference compared preoperative ( P ﹥ 0. 05), and there was no significant difference between the two groups( P ﹥ 0. 05); there was no obvious change in uric acid of the two groups, the difference was statistically significant( P ﹥ 0. 05) . Conclusion There is a certain effect of isoflurane anesthesia on blood glucose, there is no significant effect on the triglyceride, and there is protective effect of isoflurane on the kidney.关键词
异氟烷/颅脑外伤/血糖/血脂/肾功能Key words
isoflurane/brain injury/blood glucose/lipids/renal function分类
医药卫生
