中国药业2016,Vol.25Issue(12):19-21,22,4.
西洋参三七黄芪胶囊的制剂工艺研究
Preparation of Xiyangshen Sanqi Huangqi Capsule
摘要
Abstract
Objective To optimize the preparation technology of Xiyangshen Sanqi Huangqi Capsule. Methods With the formulation,an-gle of repose,bulk density,percentage of moisture absorption,and critical relative humidity as index,the suitable excipients and matching were selected,the type and filling capacity of capsule were chosen by single factor method. Results The optimal granulating technology was as following:the ratio of the Xiyangshen powder,Sanqi powder,Huangqi extract to starch was 11 :11 :16 :5,20 mesh;The parti-cles on the system of liquidity is moderate,critical relative humidity of 65%,bulk density of 0. 502 6 g/mL,capsule 0,capsule weight of 0. 35 g. Conclusion The formulation technology is stable,reasonable,and can provide reliable basis for mass production.关键词
西洋参三七黄芪胶囊/制剂工艺/临界相对湿度Key words
Xiyangshen Sanqi Huangqi Capsule/preparation technology/critical relative humidity分类
医药卫生引用本文复制引用
王贤英,谢香菊,王钧,李胜容..西洋参三七黄芪胶囊的制剂工艺研究[J].中国药业,2016,25(12):19-21,22,4.基金项目
重庆市科技计划项目,项目编号cstc2013yykfA0239。 ()