摘要
Abstract
Objective To analyze the clinical efficacy and safety of reduced glutathione sodium ( GSH ) in the treatment of liver function damage caused by acute infectious diseases in children. Methods 100 cases of children with liver function damage caused by acute infectious diseases were randomly divided into observation group and control group, 50 cases in each group. The control group was given conventional treatment, including antibiotic resistant infection, liver protection and so on; the observation group was treated with GSH treatment on the basis of the routine treatment. The effective rates of the two groups of children after 1 week of treatment, index of liv-er function improvement, recovery time and the incidence of complications were compared. Results The effective rate of the observation group was 98. 00%, which was higher than 86. 00% of the control group, the difference was statistically significant ( P < 0. 05 ) . The ALT, AST and γ-GT in the observation group and the control group had significant difference after treatment ( P < 0. 05 ) , the observa-tion group was significantly improved, and the time of recovering to normal level in the observation group was shorter than the control group , the difference was statistically significant ( P < 0. 05 ) . The complication incidence rate of the observation group was 8. 00%( 4 /50 ) , which had no significant difference with 6. 00% ( 3/50 ) of the control group ( P > 0. 05 ) . Conclusion GSH in the treatment of liver function damage in children caused by acute infectious disease can effectively improve the treatment effect, shorten the recovery time and has high security.关键词
还原型谷胱甘肽钠/小儿急性感染性疾病/肝功能损害Key words
reduced glutathione sodium/children with acute infectious disease/liver function damage分类
医药卫生
