中国医药科学2016，Vol.6Issue(9)：201-203,213,4.
大量输注悬浮红细胞对手术患者凝血功能的影响
The effect of large amount of suspended red blood cell transfusion on blood coagulation function in patients with surgery
郭鹏豪 1杨小立2
作者信息
- 1. 广东省东莞市中心血站，广东东莞 523901
- 2. 广东省东莞市第五人民医院，广东东莞 523905
- 折叠
摘要
Abstract
Objective To analyze the effects of large amount of suspended red blood cell transfusion and different injection rates between fresh plasma (FP) and red blood cell on blood coagulation function in patients with surgery. Methods 85 massive transfusion surgical patients from January 2014 to December 2015 in the fifth people''s hospital of Dongguan city were divided into observation group and control group according to the amount of suspended red blood cell transfusion. According to the ratios of plasma and suspended red blood cell transfusion, the patients were divided into high ratio group (≥1∶ 1),middle ratio group (1∶1-1∶2) and low ratio group (≤1∶2). Collecting venous blood, the hemoglobin (HGB), hematocrit (HCT) and coagulation related indicators’ changes of the before and after blood transfusion were compared. The coagulation related indicators contained platelet (PLT), fibrinogen (FIB), prothrombin time (PT), thrombin time (TT) and activated partial thromboplastin time (APTT). ResultsAfter blood transfusion of all the patients, the HGB and HCT levels were significantly increased, and the PT, TT and APTT values were dramatically prolonged. The PLT and FIB of the observation group were significantly decreased, the differences were statistically significant (allP<0.05). In the middle and low ratio group, the PLT and FIB levels were significantly decreased, while the PT, TT and APTT values were dramatically prolonged. The levels’ changes of the low ratio group were more apparent. All the differences were statistically significant (allP<0.05). Conclusion Large amount of suspended red blood cell transfusion could lead to coagulation dysfunction in surgical patients. Increasing the ratios of plasma and suspended red blood cell transfusion could relieve the coagulation dysfunction.关键词
大量输血/悬浮红细胞/凝血功能Key words
Massive blood transfusion/Suspended red blood cell/Blood coagulation function分类
医药卫生引用本文复制引用
郭鹏豪,杨小立..大量输注悬浮红细胞对手术患者凝血功能的影响[J].中国医药科学,2016,6(9):201-203,213,4.
