北京中医药大学学报2016，Vol.39Issue(7)：590-594,5.DOI:10.3969/j.issn.1006-2157.2016.07.013
四妙勇安汤中甘草苷、金丝桃苷和木犀草苷提取率的拆方分析
Decomposition analysis on extraction rate changes of liquiritin,hyperoside and luteoloside in SimiaoYong’ an Decoction
摘要
Abstract
Objective To investigate the influence of different decomposed combinations of Simiao Yong’ an Decoction ( four-ingredient health-restoring decoction ) on the extraction rates of liquiritin , hy-peroside and luteoloside .Methods The extraction rates of liquiritin , hyperoside and luteoloside were de-termined with HPLC using a SunfireTMC18 analytical column(4.6mm ×150mm,5μm) in decomposed for-mula of Simiao Yong ’ an Decoction.The mobile phase was composed of aqueous phosphoric acid (0.1%) and acetonitrile using anisocratic elution .The column temperature was 35℃.The flow rate was 1.0 mL/min while the detection wavelength was set at 276 nm(liquiritin)and 350 nm(hyperoside and luteoloside ) .The contents and the extraction rates of liquiritin , hyperoside and luteoloside from the origi-nal and dismantled formula were detected and analyzed .Results Compared with the single herb , the more ingredients it contained , the higher extraction rates of liquiritin , hyperoside and luteoloside .When the whole ingredients were stewed together , the extraction rates of these 3 components reached the peak . Conclusion The different decomposed SimiaoYong ’ an Decoction can significantly improve the extrac-tion rates of liquiritin , hyperoside and luteoloside , which indicated the validity and rationality of com-pound compatibility from the extraction rates of chemical compositions .关键词
四妙勇安汤/拆方/甘草苷/金丝桃苷/木犀草苷/提取率Key words
Simiao Yong’ an Decoction(four-ingredient keeping health decoction)/prescription disman-tlement/liquiritin/hyperoside/luteoloside/extraction rate分类
中医学引用本文复制引用
胡少伟,姜艳艳,高尧春,王翀,陈路晓,刘斌..四妙勇安汤中甘草苷、金丝桃苷和木犀草苷提取率的拆方分析[J].北京中医药大学学报,2016,39(7):590-594,5.基金项目
北京市建委共建科研基地建设项目 （）
