吉林大学学报（医学版）2016，Vol.42Issue(4)：817-820,4.DOI:10.13481/j.1671-587x.20160435
原发骨髓弥漫大 B 细胞淋巴瘤1例报告及文献复习
Primary bone marrow diffuse large B-cell lymphoma:One case report and literature review
摘要
Abstract
Objective:To analyze the diagnosis and treatment of 1 case of primary bone marrow diffuse large B cell lymphoma (DLBCL),and to provide the reference for its dignosis and treatment. Methods:Combined the medical history and other auxiliary examination results, the possibility of diagnosis of primary bone marrow lymphoma (PBML)was suspected. Bone marrow biopsy and immunohistochemistry were carried out for diagnosis, and R-CHOP (rituximab, cyclophosphamide,doxorubicin,vincristine,and prednisolone) was selected as the chemotherapy scheme. Results:The diagnostic basis of the case was in accordance with the diagnostic standard of PBML.According to the results of immunohistochemical staining,it was classified as the DLBCL subtype. Then the patient received 6 cycles of R-CHOP immune chemotherapy. Complete remission of bone marrow cell morphology was gained after the first cycle of R-CHOP treatment,and the patient was treated for another five cycles and the complete remission was retained in 3 months of follow up after drug withdrawal. Conclusion:Bone marrow biospy and immunohistochemistry have the unique diagnostic values for primary bone marrow DLBCL,and the regimens containing rituximab may provide a ideal efficacy during short term observation.关键词
原发骨髓淋巴瘤/弥漫大 B 细胞淋巴瘤/骨髓病理Key words
primary bone marrow lymphoma/diffuse large B cell lymphoma/bone marrow biopsy分类
医药卫生引用本文复制引用
张文龙,杨华,孙延霞..原发骨髓弥漫大 B 细胞淋巴瘤1例报告及文献复习[J].吉林大学学报（医学版）,2016,42(4):817-820,4.基金项目
吉林省科技厅自然科学基金资助课题 （）
