磁共振成像2016，Vol.7Issue(7)：535-540,6.DOI:10.12015/issn.1674-8034.2016.07.011
弥散频谱成像的研究进展
Research progress of diffusion spectrum imaging
摘要
Abstract
AbstractScientific studies showed that many areas in human brains contain fiber tracts running along multiple different directions, and the general average diffusion of water molecules within the image voxles of such areas does not statistically follow Gaussian distribution. Therefore, the model of diffusion tensor that hypothesizes a single fiber orientation is intrinsically defective in revealing the microstructures of brain tissues. Diffusion spectrum imaging (DSI) employs pulse sequences using multiple b-values along multiple gradient directions, sampling diffusion information of water molecules in the entire q-space, and quantitatively estimates water diffusion using a probability density function of high angular resolution diffusion imaging. DSI thus can reliably observe fibers running along multiple directions within any voxel in the image, which subsequently allows fiber tracking along different directions, leading to improved reconstruction relfecting true but complicated tissue structures in reality. This article aims to conduct a comprehensive survey of literatures published in recent years in the domain of DSI research, providing a summary on its fundamental principles, methodology, applications and important progresses, which may hopefully help promote the development of DSI in China in both research and clinical studies.关键词
弥散磁共振成像/弥散频谱成像Key words
Diffusion magnetic resonance imaging/Diffusion spectrum imaging分类
医药卫生引用本文复制引用
赵智勇,刘小征,范明霞,徐冬溶..弥散频谱成像的研究进展[J].磁共振成像,2016,7(7):535-540,6.基金项目
国家自然科学基金(编号81471734、81471651) （编号81471734、81471651）
