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The present treatment and mechanism progress of arsenic trioxide in hematological malignancies

Lin Liu Zhi-Gang Zhao

传统医学研究(英文版)2016,Vol.1Issue(3):115-121,7.
传统医学研究(英文版)2016,Vol.1Issue(3):115-121,7.

The present treatment and mechanism progress of arsenic trioxide in hematological malignancies

The present treatment and mechanism progress of arsenic trioxide in hematological malignancies

Lin Liu 1Zhi-Gang Zhao1

作者信息

  • 1. Department of Hematology and 0ncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
  • 折叠

摘要

Abstract

三氧化二砷(ATO)是一种剧毒物质,又是中药砒霜的主要成分,人类用它作为药物治疗疾病已有2400多年的历史。近年来发现ATO对急性早幼粒细胞性白血病(APL)具有显著的疗效。为进一步了解ATO治疗血液系统恶性肿瘤作用的研究近况,本文回顾ATO的研发历史,并总结其在治疗血液恶性肿瘤中的作用机制及临床应用,以期为ATO治疗肿瘤方面的研究提供新的思路。

关键词

Arsenic trioxide/Hematological malignancies/Mechanisms/Clinical application

Key words

Arsenic trioxide/Hematological malignancies/Mechanisms/Clinical application

引用本文复制引用

Lin Liu,Zhi-Gang Zhao..The present treatment and mechanism progress of arsenic trioxide in hematological malignancies[J].传统医学研究(英文版),2016,1(3):115-121,7.

传统医学研究(英文版)

2413-3973

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