南方医科大学学报2016，Vol.36Issue(7)：887-891,5.DOI:10.3969/j.issn.1673-4254.2016.07.02
胎膜早破对胎龄<37周早产儿并发症的影响
Impact of premature rupture of membranes on neonatal complications in preterm infants with gestational age<37 weeks
段顺艳 1刘卫鹏 2刘芳 3程红斌 4丁艳洁 5陈铁强 6许平 7杨李红 8吴素静 8汪瑾 9彭立 9孔祥永 1赵小林 10丘惠娴 11温伟溪 12李莹 12李楠 13文峥 13郭果 14王凤 14李改梅 2李薇 2徐凤丹 3赵晓英 1许云波 3陈文超 4尹欢 4王晓亮 4单瑞艳 5韩梅盈 5杨春燕 7封志纯 7吕红艳 1巨容 10李占魁 8曾淑娟 9武辉 11张雪峰12
作者信息
- 1. 南方医科大学陆军总医院临床医学院附属八一儿童医院极早产NICU，北京100700
- 2. 海军总医院新生儿科，北京100048
- 3. 白求恩国际和平医院新生儿科，河北石家庄050082
- 4. 黄石市妇幼保健院新生儿科，湖北 黄石 435000
- 5. 烟台毓璜顶医院新生儿科，山东 烟台 264000
- 6. 长沙市妇幼保健院新生儿科，湖南 长沙 410007
- 7. 聊城市人民医院新生儿科，山东 聊城 252000
- 8. 邯郸市妇幼保健院新生儿科，河北 邯郸 056001
- 9. 成都市妇女儿童中心医院新生儿科，四川 成都 610091
- 10. 陆军总医院附属八一儿童医院极早产NICU，北京100700
- 11. 陕西省妇幼保健院新生儿科，陕西 西安 710003
- 12. 深圳市龙岗中心医院新生儿科，广东 深圳 518116
- 13. 吉林大学第一医院新生儿科，吉林 长春 130021
- 14. 中国人民解放军第三〇二医院新生儿科，北京100039
- 折叠
摘要
Abstract
Objective To investigate the effect of premature rupture of the membrane (PROM) on neonatal complications in premature infants. Methods The registration information of 7684 preterm infants with gestational age <37 weeks were collected from the cooperative units in the task group between January 1, 2014 to December 31, 2014. Specially trained personnel from each cooperative units filled in the unified form in a standardized format to record the gender, gestational age, birth weight, PROM, placental abruption, antenatal corticosteroid, Apgar score, amniotic fluid pollution, and complications of the infants. The data were analyzed comparatively between the cases with PROM and those without (control). Results The preterm mortality rate was significantly lower but the incidences of ICH, NEC, ROP and BPD were significantly higher in PROM group than in the control group (P<0.05). The 95%confidence interval of the OR value was<1 for mortality, and was>1 for ICH, NEC, ROP and BPD. After adjustment for gestational age, birth weight, gender, mode of delivery, placental abruption, placenta previa, prenatal hormones, gestational diabetes mellitus (GDM), gestational period hypertension and 5-min Apgar score <7, the incidences of NEC, ROP and BPD were significantly different between the two groups (P<0.05) with 95%confidence interval of OR value >1, but the mortality rate and incidence of ICH were not significantly different between the two groups (P>0.05). Conclusion PROM is a risk factor for NEC, ROP and BPD in preterm infants, and adequate intervention of PROM can reduce the incidences of such complications as NEC, ROP and BPD in the infants.关键词
胎膜早破/早产儿/病死率/合并症Key words
premature rupture of membranes/premature infant/mortality/complication引用本文复制引用
段顺艳,刘卫鹏,刘芳,程红斌,丁艳洁,陈铁强,许平,杨李红,吴素静,汪瑾,彭立,孔祥永,赵小林,丘惠娴,温伟溪,李莹,李楠,文峥,郭果,王凤,李改梅,李薇,徐凤丹,赵晓英,许云波,陈文超,尹欢,王晓亮,单瑞艳,韩梅盈,杨春燕,封志纯,吕红艳,巨容,李占魁,曾淑娟,武辉,张雪峰..胎膜早破对胎龄<37周早产儿并发症的影响[J].南方医科大学学报,2016,36(7):887-891,5.
