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儿童及青少年分化型甲状腺癌的临床病理特征分析

高洪波 马淋淋 邰隽 白云 宋伟 邵玉军 陈永辉 王生才 倪鑫

中国耳鼻咽喉头颈外科2016,Vol.23Issue(7):371-373,3.
中国耳鼻咽喉头颈外科2016,Vol.23Issue(7):371-373,3.DOI:10.16066/j.1672-7002.2016.07.001

儿童及青少年分化型甲状腺癌的临床病理特征分析

Clinical pathological characteristics of differentiated thyroid carcinoma in children and adolescents

高洪波 1马淋淋 1邰隽 2白云 3宋伟 1邵玉军 1陈永辉 4王生才 2倪鑫2

作者信息

  • 1. 中国核工业北京四○一医院核素诊疗中心,北京 102413
  • 2. 首都医科大学附属北京儿童医院耳鼻咽喉头颈外科,北京 100045
  • 3. 首都儿科研究所附属儿童医院病理科,北京 100020
  • 4. 中国医学科学院北京协和医院核医学科,北京 100032
  • 折叠

摘要

Abstract

OBJECTIVE To investigate the clinical pathological characteristics of differentiated thyroid carcinoma (DTC) in children and adolescents. METHODS The clinical data of 30 children and adolescents with DTC were retrospectively reviewed. Meanwhile the clinical pathological characteristics of DTC were analyzed according to patients' age and gender. RESULTS Papillary thyroid carcinoma (PTC) was found in 27 cases and follicular thyroid carcinoma (FTC) in 3 cases. The average diameter of tumors was (2.56±1.1) cm. In the group of children, the incidence of lymph node metastasis was 92.3% (12/13), pulmonary metastasis was 46.2% (6/13), and those in the group of adolescents was 88.2% (15/17) and 35.3% (6/17) respectively. Children group tended to present with more vascular invasion, thyroid capsule invasion, and invasion out of thyroid, and a higher rate of cervical lymph node metastasis (P=0.025, 0.007, 0.025, 0.033). CONCLUSION Thyroid carcinoma in childhood and adolescent has a stronger invasive feature. It is easy to local invasion, lymph node and distance metastasis.

关键词

儿童/青少年/甲状腺肿瘤/临床病理特征

Key words

Child/Adolescent/Thyroid Neoplasms/clinic pathological characteristics

引用本文复制引用

高洪波,马淋淋,邰隽,白云,宋伟,邵玉军,陈永辉,王生才,倪鑫..儿童及青少年分化型甲状腺癌的临床病理特征分析[J].中国耳鼻咽喉头颈外科,2016,23(7):371-373,3.

中国耳鼻咽喉头颈外科

OACSCDCSTPCD

1672-7002

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