口腔疾病防治2016，Vol.24Issue(8)：454-458,5.DOI:10.12016/j.issn.2096-1456.2016.08.004
应用Micro-CT研究矫治力对正畸牙齿移动及牙根吸收的影响
Micro-CT study of the influence of orthodontic force on the root resorption and orthodontic tooth movement
摘要
Abstract
Objective To analyze the tooth movement distance and root resorption in rats under different orthodon⁃tic forces, to explore the effect of orthodontic force on the root resorption during orthodontic tooth movement. Methods 64 male Sprague Dawley (SD) rats aged 10 months weighting 220⁃270 g in this study. 10 g and 30 g nickel⁃titanium closed⁃coil springs were applied mesially to the maxillary right first molars, while contralateral first molar was severed as a control. At day 3, 7, 14 and 28 after loading, the molars were extracted. The tooth movement distance and the vol⁃ume on the surface area of root resorption were measured and scaned by Micro⁃CT. Results Tooth movement gradually increased after loading. For 10 g group, 30 g group showed farther tooth movement distance with time throughout 14 days (P = 0.039), but there was a reverse result at day 28 (P<0.05). There was a significant increased in the root re⁃sorption craters between the control group and the 10 g/30 g group after 28 days of loading (P=0.004), and the deeply root resorption were observed on the 30 g group (P<0.001). Conclusion Reliable evaluation and quantitative analysis in the tooth movement and the root resorption could be done by Micro⁃CT. Tooth movement in the 10 g group was more rapid than the 30 g group, nevertheless, the root resorption craters was less reduced after 28 days loading.关键词
矫治力/牙齿移动/牙根吸收/Micro-CT/大鼠Key words
Orthodontic force/Tooth movement/Root resorption/Micro-CT/Rat分类
口腔医学引用本文复制引用
贾晓威,陈蕾,邵军,徐晓芳,袁亚娣,吴昌敬..应用Micro-CT研究矫治力对正畸牙齿移动及牙根吸收的影响[J].口腔疾病防治,2016,24(8):454-458,5.基金项目
国家自然科学基金（81300890）；广州市医药卫生科技项目 （）
