国际医药卫生导报2016，Vol.22Issue(9)：1194-1196,3.DOI:10.3760/cma.j.issn.1007-1245.2016.09.004
13C呼气试验与幽门螺杆菌抗体检测的比较研究
Comparative study on 13C breath test and helicobacter pylori antibody detection methods
摘要
Abstract
Objective To compare and value two kinds of helicobacter pylori (Hp) antibody detection reagents by using 13C breath test.Methods 41 patients with digestive tract symptoms underwent 13C breath test,at the same time,all of them were test for helicobacter pylori by 2 kinds of antibody detection reagents.Taking 13C breath test as standard,EP12-A2 made by CLSI was used to calculate 95％ confidence interval (CI) for the sensitivity or specificity,and 95％ confidence interval for the difference between paired sensitivities and specificities of two Hp antibody detection reagents mentioned above.Results 95％ confidence interval for the sensitivity or specificity of reagent 1 were [26.8％,73.2％] and [87.5％,100％] respectively,while those of reagent 2 were [38.7％,83.6％] and [71.9％,96.1％] respectively.In addition,95％ confidence interval for the difference between paired sensitivities of above two reagents was [-33.7％,7.7％],while that for the difference between paired specificities was [-3.3％,28.1％].Conclusion There are no statistically significant differences in the sensitivity and specificity of two Hp antibody detection reagents,and both of them can be used for the detection and epidemiological investigation of Hp infection in clinic.关键词
幽门螺杆菌/13C呼气试验/胶体金法/EP12-A2Key words
Helicobacter pylori/13C breath test/Colloidal gold method/EP 12-A2引用本文复制引用
黄妩姣,杨佩桦,韩光,何敏,陈曲波..13C呼气试验与幽门螺杆菌抗体检测的比较研究[J].国际医药卫生导报,2016,22(9):1194-1196,3.基金项目
广东省科技计划项目(2014A020212270) （2014A020212270）
Science and Technology Program of Guangdong,China (2014A020212270) （2014A020212270）
