摘要
Abstract
Objective To investigate the risk factors of bronchopulmonary dysplasia in preterm infants,and to provide a theoretical basis for the development of clinical disease prevention strategies.Methods 172 premature infants in our hospital from June 2013 to June 2015 were selected,in whom 40 children with bronchopulmonary dysplasia were divided into case group,132 children without bronchopulmonary dysplasia were divided into control group.Compared the clinical data of two groups,and investigated risk factors of bronchopulmonary dysplasia in preterm infants through Logistic regression analysis.Results Gestational age,birth weight,hemoglobinon on the first day after birth in case group were significantly lower than those in control group,the rates of 1 min Apgar score equal to or less than 7,intrauterine infection,neonatal respiratory distress syndrome,patent ductus arteriosus,pulmonary bleeding,cytomegalovirus infection,the usage of pulmonary surfactant,receiving invasive mechanical ventilation treatment,the time of invasive mechanical ventilation equal to 7 d or above,surgical treatment,the highest inhaled oxygen volume fraction greater than or equal to 400 ml/L,receiving erythrocyte transfusion within 2 weeks after birth were significantly higher than those in control group (P＜0.05);Logistic regression analysis showed that gestational age,birth weight,cytomegalovirus infection,the time of invasive mechanical ventilation equal to 7 d or above,the highest inhaled oxygen volume fraction greater than or equal to 400 ml/L,surgical treatment,receiving erythrocyte transfusion within 2 weeks after birth were all risk factors of bronchopulmonary dysplasia in preterm infants (P＜0.05).Conclusions The incidence of bronchopulmonary dysplasia in preterm infants is caused by a variety of factors;in allusion to clinical risk factors for the onset of the disease,we should set out prevention and control measures to reduce the risk of the disease and improve the prognosis.关键词
早产儿/支气管肺发育不良/高危因素/防治策略Key words
Preterm infant/Bronchopulmonary dysplasia/Risk factor/Control strategy
