临床与病理杂志2016，Vol.36Issue(7)：1018-1023,6.DOI:10.3978/j.issn.2095-6959.2016.07.024
miRNAs在慢性阻塞性肺疾病中的研究进展
Progress in the role of miRNAs in chronic obstructive pulmonary disease
摘要
Abstract
miRNAs are small non-coding single-stranded RNAs, which regulate gene expression at posttranscriptional level through completely or partially binding to mRNA targets. Currently, more and more researches have revealed that miRNAs participates in the development of chronic obstructive pulmonary disease (COPD). This review will introduce the relationship between miRNAs and cigarette smoke exposure, emphysema, inlfammation. hTe regulating mechanism and potential clinical application of miRNAs in COPD will be highlighted.关键词
miRNA/烟草烟雾/肺气肿/炎症/慢性阻塞性肺疾病Key words
miRNAs/cigarette smoke exposure/emphysema/inlfammation/chronic obstructive pulmonary disease (COPD)引用本文复制引用
胡亭亭(综述),肖祖克(审校)..miRNAs在慢性阻塞性肺疾病中的研究进展[J].临床与病理杂志,2016,36(7):1018-1023,6.基金项目
江西省科技计划项目资助(20151BBG70121)。This work was supported by Science and Technology Project of Jiangxi Province (20151BBG70121), P. R. China （20151BBG70121）
