广西医学2016，Vol.38Issue(7)：953-955,972,4.DOI:10.11675/j.issn.0253-4304.2016.07.17
大黄为主的中药组方治疗急性百草枯中毒肺损伤前后患者肺部CT的变化
Variation of lung CT before and after treatment with Rheum officinale Baill.-based traditional Chinese medicine in patients with acute paraquat poisoning complicated with lung injury
摘要
Abstract
Objective To observe the variation of lung CT before and after treatment with Rheum officinale Baill.-based traditional Chinese medicine in patients with acute paraquat poisoning ( APP) complicated with lung injury .Methods Ninety-two patients with APP complicated with lung injury were selected,and were randomly divided into traditional Chinese medicine treatment group and routine treatment group,with 46 cases in each group.All patients received routine drug therapy and hemoperfusion.On the basis of the therapies mentioned above, the traditional Chinese medicine treatment group was orally administered paraquat poisoning detoxification after green stool disappearing .According to the time for taking poison,the variation of lung CT in both groups was observed during acute poisoning period (1 to 7 days),subacute period (8 to 14 days) and chronic period(>14 days).Results There was significant difference in the lung CT characteristics between two group in each period(P<0.05).During acute poisoning period,lung CT mainly manifested marked lung markings in the traditional Chinese medicine treatment group,and the proportion of marked lung markings was higher than that in the routine treatment group .And lung CT mainly manifested ground-glass lesions in the routine treatment group,and the proportion of ground-glass lesions was higher than that in the traditional Chinese medicine treatment group.During subacute poisoning period,lung CT mainly manifested ground-glass lesions in the traditional Chinese medicine treatment group,and the proportion of ground-glass lesions was higher than that in the routine treatment group .Pulmonary parenchymal and pulmonary interstitial changes were found in the lung CT of the routine treatment group ,and the proportions of pulmonary parenchymal and pulmonary interstitial lesions were higher than those in the traditional Chinese medicine treatment group.During chronic period,the proportion of pulmonary parenchymal lesion in the traditional Chinese medicine treatment group was higher than that in the routine treatment group ,while the proportion of pulmonary interstitial lesions was lower than that in the routine treatment group.The proportion of survival patients in the traditional Chinese medicine treatment group was higher than that in the routine treatment group(67.38%vs.39.13%,P<0.05).Conclusion Rheum officinale Baill.-based traditional Chinese medicine might alleviate lung injury and improve the prognosis in APP patients with lung injury .关键词
急性百草枯中毒/肺损伤/大黄/电子计算机断层扫描/肺部/中草药Key words
Acute paraquat poisoning/Lung injury/Rheum officinale Baill./Computed tomography/Lung/Chinese medicinal herb分类
医药卫生引用本文复制引用
徐文嫔,肖青勉,王维展,李敬,马国营,王璞,王岚,李雅琴..大黄为主的中药组方治疗急性百草枯中毒肺损伤前后患者肺部CT的变化[J].广西医学,2016,38(7):953-955,972,4.基金项目
河北省中医药管理局科研基金项目 （）
