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无创正压通气联合噻托溴铵吸入治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭

王丽萍 罗焕荣 张祥标 吴佳成

哈尔滨医药2016,Vol.36Issue(3):208-209,2.
哈尔滨医药2016,Vol.36Issue(3):208-209,2.

无创正压通气联合噻托溴铵吸入治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭

Clinical Efficacy of Tiotropium Bromide and Noninvasive Positive Pressure Ventilation in COPD Patients With Type 2 Respiratory Failure

王丽萍 1罗焕荣 1张祥标 1吴佳成1

作者信息

  • 1. 汕尾市逸挥基金医院ICU,广东 汕尾516600
  • 折叠

摘要

Abstract

Objective To evaluate the effect of tiotropium bromide and noninvasive positive pressure ventilation in COPD pa-tients with type 2 respiratory failure. Methods Standard included 67 cases of patients with stable COPD with type 2 respiratory failure were randomly divided into two groups, the control group received tiotropium bromide inhalation, the observe group received tiotropium bromide inhalation and noninvasive positive pressure ventilation, Dynamic monitoring the improvements in ventilation, oxygenation, heart rate,breath frequency. Results The clinical symptoms of observe group improved significantly after treatment began to 2 h, Compared with the control group,observe group improved significantly in blood gas indexes,heart rate,breath frequency, the difference was statistically significant (P<0. 05). The intubation rate,hospital mortality and the in hospital days were significantly lower in ob-serve group than those of control group. Its clinical efficiency has been increased as well, the difference was statistically significant ( P<0. 05). Conclusion Tiotropium bromide inhalation and noninvasive positive pressure ventilation is an effective and safe bronchodila-tor in the treating COPD patients with type 2 respiratory failure.

关键词

无创正压通气/噻托溴铵/慢性阻塞性肺疾病/呼吸衰竭

Key words

Chronic obstructive pulmonary disease/Type 2 respiratory failure/Noninvasive positive pressure ventilation/Tiotropium bromide

分类

医药卫生

引用本文复制引用

王丽萍,罗焕荣,张祥标,吴佳成..无创正压通气联合噻托溴铵吸入治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭[J].哈尔滨医药,2016,36(3):208-209,2.

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