摘要
Abstract
Objective To study the patients with type 2 diabetes and hypoglycemia and the relationship between the cognitive function. Methods between January 2013 and January 2013 in our hospital, 120 patients with type 2 diabetes mellitus in endocrinol-ogy as the research object, USES the random number table patients were randomly divided into observation group and control group. With mild cognitive dysfunction in patients with type 2 diabetes as the observation group (62 cases), without a mild cognitive dysfunc-tion in patients with type 2 diabetes for the control group (58 cases). Two groups of patients with application of general data question-naire, Montreal cognitive assessment scale on the questionnaire survey, at the same time detection of two groups of patients of glycated hemoglobin (HbA1c), fasting blood sugar (FBS), systolic blood pressure (SBP), diastolic blood pressure (DBP), high-sensitivity c-reactive protein (hs-CRP), incidence of hypoglycemia and use dynamic blood sugar monitoring and recording. Results Observa-tion group HbA1c (6. 25±1. 51), FBS (6. 23±1. 17), hypertension duration (5. 55±2. 78), (6. 86±4. 15), the duration of diabetes incidence in sugar (48. 34%), SBP, (152. 21-17. 62), the hs CRP (6. 05±2. 16) compared with control group[(7. 65±2. 45), (7. 27±1. 62),(3. 71±1. 96),(5. 11±3. 74),23. 06%,(142. 11±10. 23),(6. 21±2. 62)], the difference was statistically signifi-cant (P<0. 05), the control group the MoCA score and total score of visual space structure dimension, attention and delayed memory score was significantly lower than group, the difference was statistically significant (P< 0. 05); By the Pearson correlation analysis showed that MoCA score and total score HbA1c, FBS, SBP, hypertension, diabetes duration, duration of the hs CRP, hypoglycemia events exist different degree of negative correlation (P<0. 05) . Conclusion The risk factors of diabetic cognitive dysfunction, in pa-tients with type 2 diabetes and hypoglycemia can make the impaired cognitive function, so should be paid attention to in clinical rea-sonable early intervention in patients with type 2 diabetes treatment to delay the onset of cognitive decline.关键词
糖尿病/低血糖/认知功能障碍Key words
Diabetes/Low blood sugar/Cognitive dysfunction分类
医药卫生
