化工进展2016，Vol.35Issue(7)：2071-2079,2080,10.DOI:10.16085/j.issn.1000-6613.2016.07.019
过渡金属氧化物催化腈水合生成酰胺的研究进展
Progress on hydration of nitriles to amides catalyzed by transition metal oxides
摘要
Abstract
Hydration of nitriles to the corresponding amides has the advantages of high atomic economy and avoiding formation of undesirable side products. Traditionally,the hydration of nitriles was achieved by the catalysis of strong acid or alkali. However,it has the drawbacks of over hydrolysis of amides into carboxylic acids and the formation of salts from the neutralization of the catalysts. To overcome these difficulties various transition metal oxides including manganese dioxide (MnO2),nickel oxide (NiO),ceria (CeO2) and ruthenium hydroxide [Ru(OH)x] to replace strong acid or alkali have been used as catalysts in this reaction. In this article,the hydration of various nitriles to the corresponding amides catalyzed by the above transition metal oxides has been summarized. It can be seen that the hydration of nitriles to the amides depends on the type and preparation method of catalysts and the structure of nitriles. The preparation method,application scope,advantages and disadvantages of each catalyst are also illustrated. In addition the possible catalytic mechanisms of the catalysts are discussed. It is expected that the catalysts with excellent performance will be from complex transition metal oxides and supported metal oxides based on the above discussions.关键词
水合/腈/酰胺/过渡金属氧化物/二氧化锰/氧化镍/二氧化铈/氢氧化钌Key words
hydration/nitriles/amides/transition metal oxides/manganese dioxide/nickel oxide/ceria/ruthenium hydroxide分类
化学工程引用本文复制引用
赵晓甫,张月成,张宏宇,赵继全..过渡金属氧化物催化腈水合生成酰胺的研究进展[J].化工进展,2016,35(7):2071-2079,2080,10.基金项目
国家自然科学基金（21476057）及河北省自然科学基金（B2015202284）项目。 （）
