中国实用神经疾病杂志2016，Vol.19Issue(13)：1-2,2.
全脑灌注在脑胶质瘤边界区分中的应用价值
Application value of the whole-brain perfusion imaging on differentiating the border of glioma
摘要
Abstract
Objective To discuss the application value of the whole-brain perfusion imaging on differentiating the border of glioma. Methods The clinical data of 30 patients with glioma were retrospectively analyzed.All patients were divided into low-grade group(WHO grade Ⅰ-Ⅱ ,n= 14)and high-grade group(WHO grade Ⅲ-Ⅳ ,n= 16).The whole-brain perfusion scanning was performed to measure the imaging boundaries presented by contrast-enhanced CT and by CT perfusion in order to calculate the area.In addition ,the CBVs of the border area displayed from the whole-brain perfusion graph ,the boundary peripheral region traced by CT perfusion and the normal brain tissue in the uninjured side were measured.Results The area of the tumor acquired from CT perfusion was significantly larger than that from contrast-enhanced CT ,and the difference was statistically significant(P<0.05).CBV showed significant difference while rCBV had no difference in terms of marginal refer‐ence value of low-grade and high-grade groups.When we regarded CBV value of 1.770 0mL /100g as marginal cut-off point presented by CT perfusion in the low-grade group ,the sensitivity was 85.71% and the specificity was 78.57% .When the CBV value of 2.275 0mL/100g was determined as cut-off point in the high-grade group ,the sensitivity was 93.75% and the specificity was 93.75%.In both two groups ,the cut-off point of the rCBV value of 1.025 0 indicated that the sensitivity was 93.33% and the specificity was 83.33%.Conclusion Whole-brain perfusion imaging has a clinical effect on differentiating the border of gliomas .关键词
神经胶质瘤/全脑灌注成像/肿瘤边界Key words
Gliomas/Whole-brain perfusion imaging/Tumor border分类
临床医学引用本文复制引用
苏杭,梁新强,宾静文,吕健,陈晓武,杜成利..全脑灌注在脑胶质瘤边界区分中的应用价值[J].中国实用神经疾病杂志,2016,19(13):1-2,2.基金项目
广西自然科学基金 （）
