摘要
Abstract
Objective To analyze the relationships between central venous oxygen saturation(ScvO2 )and central venous-arterial carbon dioxide partial pressure(Pcv-aCO2 )and the prognosis of severe traumatic brain injury.Methods One hundred pa‐tients with severe traumatic brain injury admitted to ICU of our department from January 2011 to May 2014 were recrui‐ted.According to the levels of ScvO2 and Pcv-aCO2 ,we divided all patients into four groups ,in which serum markers ,general situation ,peripheral arterial blood gas and clinical outcome after 24-hour treatment were comparatively recorded and ana‐lyzed.Results The serum lactate concentration and the levels of hs-CRP and S100B proteins as well as APACHEII scores were significantly reduced in turn from group 1 to group 4 ,while lactate clearance rate ,CVP ,MAP ,PH value ,BE value ,oxygen par‐tial pressure and urine volume were significantly decreased(P<0.05).Additionally ,the hospitalization of stays ,NIHSS scores when discharged ,fatality rate of each group were also gradually reduced one by one.Conclusion ScvO2 combined with Pcv-aCO2 can effectively predict the prognosis of severe traumatic brain injury ,which have certain guiding significance for treatment .关键词
中心静脉血氧饱和度/中心静脉-动脉二氧化碳氧分压差/重型颅脑损伤/预后Key words
Central venous oxygen saturation/Central venous-arterial carbon dioxide partial pressure/Severe brain inju-ry/Prognosis分类
医药卫生
