检验医学与临床2016，Vol.13Issue(13)：1769-1771,3.DOI:10.3969/j.issn.1672-9455.2016.13.010
急性肾损伤患者 NT-proBN P与血管外肺水指数相关性研究
Association between plasma NT-proBNP and extravascular lung water index in patients with acute kidney injury
摘要
Abstract
Objective To discuss correlation between plasma N‐terminal B‐type atriuretic peptide precursor (NT‐proBNP) and extravascular lung water index (EVLWI) in patients with acute kidney injury (AKI) received mechanical ventilation .Methods A to‐tal of 80 AKI patients receiving mechanical ventilation and continuous renal replacement therapy (CRRT ) were divided into A ,B and C group ,of which serum creatinine(SCr) level gradually inreased and urinve volume decreased .Plasma NT‐proBNP ,SCr and EVL‐WI were detected before and 12 ,24 ,72 h after CRRT .Results APACHEⅡ score and SCr level were significantly different between all groups (P<0 .05) .SCr ,NT‐proBNP and EVLWI levels gradually decreased aftar CRRT ,values of which ,detected 72 h after CRRT ,were lower than values detected before CRRT (P<0 .05) .The difference between the groups was statistically significant at the same period(P<0 .05) .Before and 12 ,24 ,72 h after CRRT ,plasma NT‐proBNP were positively correlated with SCr and EVL‐WI(P<0 .05) .Conclusion Plasma NT‐proBNP and EVLWI might have correlation in AKI patients .关键词
连续性肾脏替代治疗/急性肾损伤/N末端B型钠尿肽前体/血管外肺水指数/预后Key words
continuous renal replacement therapy/acute kidney injury/N-terminal B-type atriuretic peptide precursor/ex-travascular lung water index/prognosis引用本文复制引用
谢晓红,麦叶,魏晓芬,周忠义,李娜,李瑞..急性肾损伤患者 NT-proBN P与血管外肺水指数相关性研究[J].检验医学与临床,2016,13(13):1769-1771,3.基金项目
2014年海南省科委自然科学基金项目（814321）。 （）
