检验医学与临床2016，Vol.13Issue(14)：1905-1907,3.DOI:10.3969/j.issn.1672-9455.2016.14.001
洛阳地区女性HPV感染及病毒亚型分布特征研究
HPV infection and genotypes analysis in Luoyang
摘要
Abstract
Objective To investigate the infection and genotype character of human papilloma virus (HPV ) in females of Luoy‐ang .Methods Results of HPV genotyping of 1 755 female outpatients in Gynecology Clinic of this hospital ,from June 2013 to Au‐gust 2015 ,were analyzed .Results Among 1 755 cases ,658 cases were positive with HPV ,with positive rate of 37 .5% ,high risk‐HPV infection rate of 32 .3% .Single genotype infection rate was 66 .6% ,and multiple genotypes infection rate was 33 .4% .In the positive cases ,68 .2% was high risk‐HPV infection ,and the single infection rate was 62 .3% .The top five common HPV subtypes were HPV16(27 .7% ) ,52(13 .4% ) ,81(11 .2% ) ,53(10 .3% ) and 58(9 .0% ) .The HPV positive rates in <20 ,20 - <30 ,30 - <40 ,40- <50 ,50- <60 and ≥60 years group were 40 .0% ,42 .7% ,34 .3% ,34 .7% ,43 .7% and 38 .0% ,and high risk‐HPV posi‐tive rates were 40 .0% ,34 .9% ,29 .4% ,30 .3% ,38 .0% and 34 .2% .Conclusion Females in this region could be with high HPV infection rate ,with dominant single genotype infection .In HPV positive cases ,high risk‐HPV infection might be more common ,and single high risk‐HPV infection might account for a large proportion .The most common HPV genotypes could be HPV16 and HPV52 .HPV infection might be associated with age ,and females of 50 - <60 years old could be with the highest HPV infection rate .关键词
人乳头瘤病毒/基因分型/宫颈癌/洛阳Key words
HPV/gene subtypes/cervical cancer/Luoyang引用本文复制引用
王小利,常永超,刘海花,刘刚..洛阳地区女性HPV感染及病毒亚型分布特征研究[J].检验医学与临床,2016,13(14):1905-1907,3.基金项目
国家自然科学基金资助项目（U1204821）。 （）
