检验医学与临床2016,Vol.13Issue(14):1917-1918,1921,3.DOI:10.3969/j.issn.1672-9455.2016.14.005
结核分枝杆菌蛋白抗原诊断试剂的临床价值研究
Clinical value of a diagnostic reagent for mycobacterium tuberculosis special antigen
摘要
Abstract
Objective To research and evaluate the clinical value of a diagnostic reagent for tuberculosis (TB) antibodies based on mycobacterium tuberculosis special antigen (TB‐SA) .Methods Serum levels of TB‐SA of TB group ,non‐TB respiratory disease group and healthy control group were detected by immune colloidal gold technique .Results The sensitivity of TB‐SA for detection of TB was 72 .2% and the specificity was 95 .8% .The positive rate of TB‐SA antibodies (72 .2% ) was higher than sputum smear (44 .9% ) and culture (37 .1% ) ,the differences had statistical significance(P<0 .05) .Conclusion The TB‐SA antibody detection has high sensitivity and specificity ,which has good clinical application value for diagnosis and differential diagnosis of TB .关键词
结核分枝杆菌/结核分枝杆菌蛋白抗原/诊断/免疫胶体金技术Key words
mycobacterium tuberculosis/tuberculosis special antigen/diagnosis/immune colloidal gold technique引用本文复制引用
罗槑,徐园红,朱玛,曾义岚,刘勇,罗东霞,吴桂辉..结核分枝杆菌蛋白抗原诊断试剂的临床价值研究[J].检验医学与临床,2016,13(14):1917-1918,1921,3.基金项目
四川省医学科研青年创新课题(Q14021);成都市科技惠民应用示范项目(2014-HM01-00371-SF)。 ()