检验医学与临床2016，Vol.13Issue(14)：1943-1945,3.DOI:10.3969/j.issn.1672-9455.2016.14.015
低分子肝素钠联合硫酸镁对重度子痫前期患者血清高敏C反应蛋白和D-二聚体的影响分析
Effects of low molecular weight heparin sodium combined with Magnesium sulfate on the serum hypersensitive C-reactive protein and D-dimer in patients with severe preeclampsia
马立苹 1陈媛媛 1张西艺 1李维玲1
作者信息
- 1. 陕西省西安市高新医院妇产科 710075
- 折叠
摘要
Abstract
Objective To investigate the effect of low molecular weight heparin sodium combined with Magnesium sulfate on se‐rum hypersensitive C‐reactive protein (hs‐CRP) ,D‐dimer (D‐D) in patients with severe preeclampsia .Methods A total of 100 pa‐tients with severe preeclampsia were selected in the hospital ,which were divided into observation group (50 cases) and control group (50 cases) randomly .And the control group was treated with magnesium sulfate ,the observation group was treated with low molecular weight heparin sodium combined with magnesium sulfate .The changes of hs‐CRP ,D‐D ,systolic blood pressure and dias‐tolic blood pressure were observed before and after treatment in the two groups .The average treatment time ,the time of termination of pregnancy ,the clinical efficacy and the incidence of complications were compared .Results After treatment ,hs‐CRP ,D‐D levels in the observation group were significantly lower than those in the control group (P< 0 .05) .Systolic blood pressure and diastolic blood pressure were also lower than those in control group ,there was statistically significant difference(P<0 .05) .Meanwhile ,the average treatment time of observation group and the time of termination of pregnancy were shorter than the control group ,and the difference was statistically significant (P<0 .05) .The total effective rate in the observation group [96 .00% (48/50)] was signifi‐cantly higher than that in the control group[74 .00% (37/50)](P<0 .05) ,and the incidence of complications [6 .00% (3/50)] was also significantly lower than that of the control group[24 .00% (12/50)](P<0 .05) .Conclusion Low molecular weight heparin so‐dium combined with magnesium sulfate can effectively reduce hs‐CRP and D‐D levels in patients with severe preeclampsia ,and in‐hibit the inflammatory response ,which could also improve the prognosis of newborns and be worthy of clinical application .关键词
高敏C反应蛋白/D-二聚体/重度子痫前期Key words
hypersensitive C-reactive protein/D-dimer/severe preeclampsia引用本文复制引用
马立苹,陈媛媛,张西艺,李维玲..低分子肝素钠联合硫酸镁对重度子痫前期患者血清高敏C反应蛋白和D-二聚体的影响分析[J].检验医学与临床,2016,13(14):1943-1945,3.
