国际眼科杂志2016，Vol.16Issue(8)：1477-1479,3.DOI:10.3980/j.issn.1672-5123.2016.8.18
低氧诱导因子－1α在视网膜母细胞瘤发生发展中作用的研究进展
Role of hypoxia-inducible factor-1 alpha in retinoblastoma development
摘要
Abstract
?Retinoblastoma is a common eye malignant tumor which has high degree of malignancy.The traditional treatment methods are destructive, and the prognosis is poor. Hypoxia-inducible factor-1αhighly express in retinoblastoma and regulate the development and progression of retinoblastoma ( by influencing the proliferation and differentiation of tumor cells and involving in the generation of vascular mimicry ) . This article reviewed the role of hypoxia inducible factor-1αin the development of retinoblastoma which will initiate a new avenue for the treatment of retinoblastoma.关键词
低氧诱导因子-1α/视网膜母细胞瘤/血管生成拟态Key words
hypoxia -inducible factor -1 alpha/retinoblastoma/vascular mimicry引用本文复制引用
胡佳丽,高玉..低氧诱导因子－1α在视网膜母细胞瘤发生发展中作用的研究进展[J].国际眼科杂志,2016,16(8):1477-1479,3.基金项目
上海市卫生和计划生育委员会科研资助课题（ No．201540304）@@@@The Research Foundation of Shanghai Municipal Commission of Health and Family Planning （）
