畜牧与饲料科学2016，Vol.37Issue(6)：12-15,4.
丁酸梭菌及荔枝多酚联合应用对腹泻小鼠抗氧化功能的影响
Effect of Combined Application of Clostridium butyricum and Lichee Polyphenols on Antioxidant Function of Diarrhea Mice
摘要
Abstract
This study aimed to evaluate the regulative effects of combined use of Clostridium butyricum and lichee polyphenol on redox state of mice. The blank group, diarrhea model group, lichee polyphenol group, Clostridium butyricum group and low, moderate and high dosage of lichee polyphenol and Clostridium butyricum mixture groups were included in present study. From the 1st to 10th day of the experimental period, the mice were administered for prevention and therapy purpose. At the 5th day, the diarrhea model in mice was prepared by intragastrical administration of folium sennae decoction. At the 10th day, the serum MDA content, SOD activity, GSH content and MPO activity in intestinal tissue were assessed. The results revealed that the antioxidant capacity of the diarrhea mice was reduced and the inflammation in intestinal tissue was observed;The different dosages of lichee polyphenol and Clostridium butyricum mixture was able to reduce the content of oxidation products MDA, improve the activity of reductase SOD, stimulate the generation of reducing substances GSH, and inhibit the inflammation. The optimum effect was observed in moderate dosage group. It is demonstrated that the combined application of Clostridium butyricum and lichee polyphenols was able to improve the antioxidant capacity of the diarrhea mice and they have synergistic effect.关键词
丁酸梭菌/荔枝多酚/番泻叶/腹泻/抗氧化Key words
Clostridium butyricum/lichee polyphenol/folium sennae/diarrhea/antioxidant分类
农业科技引用本文复制引用
涂杜,谭富英,徐志宏..丁酸梭菌及荔枝多酚联合应用对腹泻小鼠抗氧化功能的影响[J].畜牧与饲料科学,2016,37(6):12-15,4.基金项目
广东省科技计划项目（2015A020209080）；广州市科技计划项目（201604020138）。 （）
