水生生物学报2016，Vol.40Issue(4)：793-803,11.DOI:10.7541/2016.103
饲料氧化鱼油对草鱼肝胰脏结构和功能的损伤
DAMAGE OF OXIDIZED FISH OIL ON THE STRUCTURE AND FUNCTION OF HEPATOPANCREAS OF GRASS CARP (CTENOPHARYNGODON IDELLUS)
摘要
Abstract
To investigate effects of oxidized fish oil on the structure and permeability of hepatopancreas of grass carp (Ctenopharyngodon idellus), five iso-nitrogen and iso-energy diets were formulated with soybean oil, fish oil and oxi-dized fish oil at different concentrations, 6%fish oil, 6%soybean oil, 2%oxidized fish oil and 4%soybean oil, 4%oxi-dized fish oil and 2%soybean oil, 6%oxidized fish oil for a 72d experiment. Result showed that oxidized fish oil signi-ficantly increased (P<0.05) the content of ALB, GLB, MDA, GSH of grass carp serum and significantly reduced (P<0.05) the content of GSH, SOD of grass carp hepatopancreas. Oxidized fish oil significantly increased (P<0.05) the HSI, content of lipid of hepatopancreas and TG content of serum, and significantly reduced (P<0.05) the ratio of HDL and LDL at the same time. Oxidized fish oil significantly enhanced the content of TC on serum and hepatopancreas and the content of TBA on hepatopancreas (P<0.05) but significantly diminished the content of serum TBA (P<0.05). Oxi-dized fish oil caused fatty liver by disrupting the fat metabolism, mitochondrial damage of hepatopancreas by impact-ing bile acid accumulation, hepatopancreas cell fibrosis, and tissue atrophyin grass carp. In conclusion, products of oxi-dized fish oil may cause grass carp oxidative stress and decrease antioxidant capacity of grass carp hepatopancreas.关键词
脂肪代谢/胆汁酸/线粒体/草鱼Key words
Fat Metabolism/Bile Acid/Mitochondrial/Ctenopharyngodon idellus分类
农业科技引用本文复制引用
陈科全,萧培珍,叶元土,蔡春芳,吴萍,黄雨薇,吴韬,林秀秀,罗其刚,张宝彤..饲料氧化鱼油对草鱼肝胰脏结构和功能的损伤[J].水生生物学报,2016,40(4):793-803,11.基金项目
国家自然科学基金项目(31172417) （31172417）
苏州市应用基础研究项目(SYN201316)资助[Supported by the National Natural Science Foundation of China (31172417) （SYN201316）
Applied Basic Research Programs of Suzhou City (SYN201316)] （SYN201316）
