水生生物学报2016，Vol.40Issue(4)：804-813,10.DOI:10.7541/2016.104
饲料氧化鱼油引起草鱼肠道结构损伤、通透性增加
EFFECTS OF DIETARY OXIDIZED FISH OIL ON THE INTESTINAL STRUCTURE AND PERMEABILITY OF GRASS CARP (CTENOPHARYNGODON IDELLUS)
摘要
Abstract
To investigate effects of oxidized fish oil on the structure and permeability of intestine of grass carp (Cteno-pharyngodon idellus), five iso-nitrogen and iso-energy diets were formulated with soybean oil, fish oil and oxidized fish oil at different concentrations:6%fish oil, 6%soybean oil, 2%oxidized fish oil and 4%soybean oil, 4%oxidized fish oil, and 2%soybean oil, 6%oxidized fish oil, respectively. Compared with the 6%soybean oil, the oxidative product of fish oil at low level increased serum and intestine MDA and GSH content but diminished the GSH content at high level. The oxidized fish oil significantly reduced intestine bile acid content (P<0.05). The oxidized fish oil en-hanced the number of goblet cell (P<0.05), The microvilli of intestine was enlarged by low oxidized fish oil level and atrophied by high level. Serum D-lactic acid and endotoxin content increased significantly by oxidized fish oil because of the enlarged gap between tight junction, the hyperplasia and edema of villi. Thus, the oxidized fish oil might damage the intestinal epithelial tight junction and destroy the intestinal mucosal epithelium, which would increase intestinal oxidative stress and interfere the bile acids-cholesterol circulation of grass carp.关键词
氧化鱼油/肠道/结构/通透性/草鱼Key words
Dxidized fish oil/Intestine/Structure/Permeability/Ctenopharyngodon idellus分类
农业科技引用本文复制引用
陈科全,萧培珍,叶元土,蔡春芳,吴萍,黄雨薇,吴韬,林秀秀,罗其刚,张宝彤..饲料氧化鱼油引起草鱼肠道结构损伤、通透性增加[J].水生生物学报,2016,40(4):804-813,10.基金项目
国家自然科学基金项目(31172417) （31172417）
苏州市应用基础研究项目(SYN201316)资助[Supported by the National Natural Science Foundation of China (31172417) （SYN201316）
Applied Basic Research Programs of Suzhou City (SYN201316)] （SYN201316）
