沈阳医学院学报2016，Vol.18Issue(4)：276-278,3.DOI:10.16753/j.cnki.1008-2344.2016.04.017
一氧化氮吸入治疗新生儿持续肺动脉高压的效果观察及护理
Clinical Efficacy of Inhaled Nitric Oxide in the Treatment of Persistent Pulmonary Hypertension of the Newborn and Nursing
摘要
Abstract
Objective:To analysis clinical efficacy of inhaled nitric oxide in the treatment of persistent pulmonary hypertension of the newborn and nursing. Methods: A total of 84 cases of persistent pulmonary hypertension of the newborn received high-frequency oscillation mode of mechanical ventilation at higher ventilation parameters,and inhaled nitric oxide therapy. Before inhalation of nitric oxide and 30 min, 24 h after inhalation of nitric oxide, transcutaneous oxygen saturation (SpO2), blood gas analysis,blood pressure,heart rate,mean arterial blood pressure and oxygenation index (OI) were recorded. Results:There was significant difference in SpO2,PaO2,PaCO2,FiO2,OI at 30 min and 24 h after inhalation of nitric oxide (P<0.05) . There was no significant difference in HR,SPAP,SBP,MAP,pH (P>0.05) .Conclusion:Inhaled nitric oxide combined with a high-frequency oscillation mode of mechanical ventilation in newborns with persistent pulmonary hypertension significantly improve OI,blood gas analysis,oxygen saturation and other indicators,and effective interventions can avoid nitric oxide-related adverse reactions.关键词
一氧化氮/新生儿/持续肺动脉高压/临床疗效/护理措施Key words
nitric oxide/newborn/persistent pulmonary hypertension/clinical efficacy/nursing分类
医药卫生引用本文复制引用
林玉,林小燕..一氧化氮吸入治疗新生儿持续肺动脉高压的效果观察及护理[J].沈阳医学院学报,2016,18(4):276-278,3.基金项目
茂名市科技计划项目 （）
