实用医学杂志2016，Vol.32Issue(11)：1868-1870,3.DOI:10.3969/j.issn.1006-5725.2016.11.044
中医体质分型对丙泊酚靶控输注药效学的影响
The pharmacodynamics effect of propofol target-injection on different TCM physique types
摘要
Abstract
Objective Investigate the effect of EC50 of propofol target-injection in the different TCM (traditional Chinese medicine) physique types of patients who are in unconscious phase. Methods Depend on the standard protocol of "TCM physique types sort and determination", we sorted 60 patients into three groups:Ping He (group A), Yang Xu (group B) and Yin Xu (group C), 20 patients per group. We applied the sequential experiment to measure the minimal EC50 and NI values of propofol when the patients were in the unconscious phase. Results The EC50 of propofol of group A, B and C are 3.85 μg/mL, 4.12 μg/mL and 3.43 μg/mL respectively. 95% confidence intervals of group A, B and C are 3.64 ~ 4.07 μg/mL, 3.92 ~ 4.33μg/mL and 3.26 ~ 3.60 μg/mL respectively. Conclusion There is a correlation between the different TCM physique types and the dosage of propofol target-injection.关键词
丙泊酚/中医体质分型/剂量效应关系/靶控输注Key words
Propofol/Traditional Chinese Medicine (TCM) physique types/Dosage-response relationship引用本文复制引用
秦凯,李宇国,李金峰,杨硕,谢晓澜,钟敏,肖建斌..中医体质分型对丙泊酚靶控输注药效学的影响[J].实用医学杂志,2016,32(11):1868-1870,3.基金项目
广东省中医药管理局基金资助项目 （）
