实用医学杂志2016,Vol.32Issue(12):1941-1944,4.DOI:10.3969/j.issn.1006-5725.2016.12.014
声辐射力脉冲成像技术在2型糖尿病合并非酒精性脂肪肝病患者的应用
A pilot clinical study on quantitative evaluating the degree of diffuse fatty liver by acoustic radiation ;force impulse imaging in patients with T2DM complicated with NAFLD
摘要
Abstract
Objective To investigate the influencing factors of the controlled virtual touch tissue quantification (VTQ) in liver of patients with type 2 diabetes mellitus (T2DM) complicated withnon-alcoholic fatty liver disease (NAFLD). Methods Two hundred and twenty-seven patients with T2DM complicated with NAFLD were enrolled in this study,and the shear wave speed of the liver was measured by VTQ. Levels of the fasting plasma glucose, glycated hemoglobin,total cholesterol three acids glyceride, low density lipoprotein, high density lipoprotein , aspertate aminotransferase , alanine aminotransferase , gamma glutamyl transpeptidase and uric acid were measured. The relationships among VTQ and the severity of NAFLD , and those quantitative indexes were analyzed. Results Univariate analysis showed that the value of shear wave speed was negatively correlated with age,duration of diabetes,INS and HDL-C,while was positively correlated with HbA1c and AST. Conclusion Age, sex and levels of serum HbA1c,INS,AST and HLD-C might affect the values of shear wave speed in patients with T2DM complicated with NAFLD.关键词
糖尿病,2型/非酒精性脂肪肝/声辐射力脉冲成像/相关性分析Key words
Diabetes mellitus Type 2/Non-alcoholic fatty liver disease/Acoustic Radiation Force Impulse-imaging/Correlation analysis引用本文复制引用
魏华,岑欢,卢颖,张建兴,陈冰丽..声辐射力脉冲成像技术在2型糖尿病合并非酒精性脂肪肝病患者的应用[J].实用医学杂志,2016,32(12):1941-1944,4.基金项目
广东省科技厅计划项目 ()