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卵泡刺激素受体基因多态性与卵巢过度刺激综合征的相关性

沈亚 陈丽 谭小方 张晶晶 施蔚虹

实用医学杂志2016,Vol.32Issue(12):1994-1996,1997,4.
实用医学杂志2016,Vol.32Issue(12):1994-1996,1997,4.DOI:10.3969/j.issn.1006-5725.2016.12.030

卵泡刺激素受体基因多态性与卵巢过度刺激综合征的相关性

Correlation between the follicle-stimulating hormone receptor gene polymorphism and the ovarian ;hyperstimulation syndrome

沈亚 1陈丽 1谭小方 1张晶晶 1施蔚虹1

作者信息

  • 1. 226000 江苏省南通市妇幼保健院生殖中心
  • 折叠

摘要

Abstract

Objective To investigate the relationship between OHSS and FSHR gene polymorphism. Methods Two hundred and two women were enrolled in this study. The FSHR gene polymorphisms at position 307 and 680 were detected. Results The distribution of the allele frequency and genotype frequency of the position 680 in FSHR gene were significantly different between women with OHSS or not. No significant differences of the position 307 in FSHR gene were observed. Conclusion Themutation of Asn680Ser in FSHR might be closely related with OHSS.

关键词

卵泡刺激素受体/卵巢过度刺激综合征/单核苷酸基因多态性

Key words

Follicle-stimulating hormone receptor/Ovarian hyperstimulation syndrome/Single nucleotide polymorphism

引用本文复制引用

沈亚,陈丽,谭小方,张晶晶,施蔚虹..卵泡刺激素受体基因多态性与卵巢过度刺激综合征的相关性[J].实用医学杂志,2016,32(12):1994-1996,1997,4.

基金项目

南通市社会事业科技创新与示范项目 ()

实用医学杂志

OA北大核心CSTPCD

1006-5725

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