中国组织工程研究2016，Vol.20Issue(31)：4671-4676,6.DOI:10.3969/j.issn.2095-4344.2016.31.016
新型可灌注骨水泥椎弓根螺钉的生物力学性能及在骨质疏松性腰椎退变中的应用
Biomechanical properties of a novel pourable cement pedicle screw and its application to osteoporotic lumbar degeneration
刘扬 1刘丹 1肖运祥 1陈海丹 1赵红卫1
作者信息
- 1. 三峡大学第一临床医学院，宜昌市中心人民医院脊柱外科，三峡大学脊柱医学与创伤研究所，湖北省宜昌市 443000
- 折叠
摘要
Abstract
BACKGROUND:Fragile bone in senile osteoporosis patients easily weakened pedicle screw fixation capacity. Therefore, bone cement leakage and screw removal cannot be solved during pedicle screw repair in osteoporotic patients with degenerative lumbar spine. OBJECTIVE:To investigate the biomechanical properties of novel pourable pedicle screws and bone cement application effect in osteoporotic patients with degenerative lumbar spine. METHODS:Six lumbar specimens (T11-L5) at the mean age of (72.9±4.2) years were selected, total y 42 vertebrae. The average bone density was 0.696 g/cm2. Any side of al vertebrae was inserted with pourable pedicle screws. 2 mL of bone cement was perfused under the X-ray fluoroscopy with cement push rod and fil ing cylinder. The same number of conventional screws was inserted into the opposite side of the samples. Three-point bending test was performed in two kinds of screws. The maximum vertebral axial pul out force test and the maximum spin torque test were conducted in vertebra to observe the destruction of the vertebral body and implanted effect. RESULTS AND CONCLUSION:(1) The ultimate strength and yield load of novel pourable cement pedicle screws were significantly more than conventional screws (P<0.05). Ultimate displacement and yield displacement were significantly less in novel pourable cement pedicle screws than in conventional screws (P<0.05). (2) The maximum vertebral axial pul out force and the maximum spin torque were significantly higher in novel pourable pedicle screws than in conventional screws (P<0.05). (3) In summary, novel pourable cement pedicle screw is simple to operate, can effectively control bone cement penetration, and improve screw stability in osteoporotic vertebrae. Moreover, after treatment, the removal of screws is convenient, cannot evidently destroy vertebral body or screw channel, and promote early recovery.关键词
骨科植入物/脊柱植入物/骨质疏松/腰椎退变/骨水泥/椎弓根螺钉/生物力学/轴向拔出力/旋出力矩/稳定性Key words
Lumbar Vertebrae/Osteoporosis/Biomechanics/Tissue Engineering分类
医药卫生引用本文复制引用
刘扬,刘丹,肖运祥,陈海丹,赵红卫..新型可灌注骨水泥椎弓根螺钉的生物力学性能及在骨质疏松性腰椎退变中的应用[J].中国组织工程研究,2016,20(31):4671-4676,6.
