现代医药卫生2016，Vol.32Issue(13)：1994-1996,2000,4.DOI:10.3969/j.issn.1009-5519.2016.13.014
磁共振扩散加权成像对胰腺癌的诊断价值探讨
Study on diagnostic value of DWI in pancreatic carcinoma
罗丽 1韩福刚 1舒健1
作者信息
- 1. 泸州医学院附属医院放射科，四川泸州646000
- 折叠
摘要
Abstract
Objective To analyze the diagnostic value of magnetic resonance diffusion-weighted imaging (DWI) and ap parent diffusion coefficient(ADC) in pancreatic carcinoma. Methods The imaging data in 37 patients with pancreatic carcinoma undergoing routine MRI,DWI and enhancement scanning in our hospital from May 2009 to November 2010 were retrospectively analyzed,including 28 cases of pancreatic head carcinoma,3 cases of pancreatic neck carcinoma and 6 cases of pancreatic body and tail carcinoma. Contemporaneous 32 patients with upper abdominal examination (excluding pancreatic diseases by clinical, imaging and laboratory detection) were selected as the control group. The Philips 1.5 T or 3.0 T superconduction MR scanner was adopted to conduct routine MRI and DWI scanning for analyzing the DWI imaging manifestations of pancreatic carcinoma;The ADC values of pancreatic carcinoma,pericancerous tissue and normal pancreas were measured and analyzed by using the one way Anova. The receiver operating characteristic(ROC) curve was drawn to determine the best diagnostic threshold,then their diagnos-tic value was judged,and the sensitivity,specificity and accuracy of ADC for diagnosing pancreatic carcinoma were calculated. Results All 37 cases of pancreatic carcinoma tissue displayed hyperintensity signal on DWI sequence. The mean ADC values of cancer,pericancerous tissue and normal pancreas were(1.470±0.188)×10-3,(1.571±0.175)×10-3,(1.683±0.169)×10-3 mm2/s re-spectively,showing statistical different among them(F=12.207,P<0.01). The sensitivity and specificity of the best diagnostic threshold(ADC=1.503×10-3 mm2/s) for diagnosing pancreatic carcinoma were 78.38%and 87.50%respectively. The area under the ROC curve was 0.817,which had the middle diagnostic value. Conclusion Pancreatic carcinoma tissue displays hyperinten-sity signal on DWI sequence. There is obvious difference in average ADC value between pancreatic carcinoma tissue and normal pancreatic tissue. So the measure of ADC may contribute to diagnose pancreatic carcinoma.关键词
磁共振成像/磁共振波谱学/胰腺肿瘤/诊断/扩散加权成像Key words
Magnetic resonance imaging/Magnetic resonance spectroscopy/Pancreatic neoplasms/diagnosis/diffusion weighted imaging引用本文复制引用
罗丽,韩福刚,舒健..磁共振扩散加权成像对胰腺癌的诊断价值探讨[J].现代医药卫生,2016,32(13):1994-1996,2000,4.
