中国医疗设备2016，Vol.31Issue(7)：22-25,29,5.DOI:10.3969/j.issn.1674-1633.2016.07.007
超低剂量对比剂主动脉CTA检查联合单能量成像和ASIR技术的可行性
Study on the Feasibility of Application of Aortic CT Angiography with Ultra-Low Volume Contrast Medium in Optimal Monochromatic Images of Spectral CT with ASIR Reconstruction
侯平 1刘杰 1蒋耀军 1高剑波 1石明国2
作者信息
- 1. 郑州大学第一附属医院放射科，河南 郑州 450052
- 2. 第四军医大学西京医院放射科，陕西西安710032
- 折叠
摘要
Abstract
Objective To evaluate the vascular enhancement and image quality of ultra-low volume contrast medium at aortic CT angiography by using monochromatic images of spectral CT with ASIR reconstruction, in compared with conventional 120 kvp scan with 70 mL contrast medium. Methods Altogether 62 patients who underwent aorta CTA examination on a spectral CT scanner were evenly and randomLy divided into 2 groups: Experiment Group and Control Group. Experiment Group was scanned by using GSI mode with contrast agent volume of 0.4 mL/kg and injection rate calculated as volume/(delay time+exposure time). After the examination, images using 55 keV (with 50%ASIR) and 70 keV (with filtered back projection, FBP) were reconstructed. Those two sets of images were regarded as Group A and B. Control Group was scanned by using 120 kVp with contrast agent volume of 70 mL and 5 mL/s injection rate. The obtained images using filtered back projection (FBP) were regarded as Group C. CT values and CNR of aorta and its branches were obtained and compared. Results were statistically analyzed by single-factor analysis of variance and Bonferroni correction among three groups. The subjective rating score among the three groups was compared by using Kruskal-WallisH test. Results CNR values obtained in Group A, B and C were (18.1±5.8) vs (12.1±4.0) vs (13.2±1.8) in ascending aorta; (18.3±5.8) vs (12.1±3.8) vs (12.3±1.8) in descending aorta;(16.8±4.4) vs (11.5±3.7) vs (12.4±2.1) in celiac trunk;(17.2±4.7) vs (11.6±3.2) vs (12.5±1.9) in renal arteries, with signiifcant differences among the three groups (P values<0.05). CT values for aorta and its branches were [(358±69), (213±91) and (374±34) HU in ascending aorta;(361±64), (216±37) and (353±30) HU in descending aorta;(336±55), (205±34) and (354±36) HU in celiac trunk;(333±54), (201±34) and (356±54) HU in renal arteries for Group A, B and C respectively, with signiifcant differences among the three groups (P=0.00) and between Group A and B, Group B and C (P=0.00). There was no signiifcant difference between Group A and C (P>0.05). The amount of contrast agent for each patient in Experiment Group was (28.8±4.4) mL, while that in Control Group was 70 mL. There were signiifcant differences of the contrast medium volume between the two groups (F=537.09, P=0.00). And the contrast injection lfow rate for each patient in Control Group and Experiment Group was 5.0 mL/s and (2.4±0.3) mL/s, respectively, with significant differences between the groups (P=0.000). Conclusion Monochromatic images of 55 keV with 50%ASIR in spectral aortic CTA using ultra-low volume contrast medium was feasible. Compared with conventional 120 kVp scan, it could signiifcantly reduce the amount of contrast agent and injection rate by 60%with improved image quality.关键词
主动脉/X线计算机/体层摄影术/造影剂Key words
aorta/X-ray computer/computerized tomography/contrast agent分类
医药卫生引用本文复制引用
侯平,刘杰,蒋耀军,高剑波,石明国..超低剂量对比剂主动脉CTA检查联合单能量成像和ASIR技术的可行性[J].中国医疗设备,2016,31(7):22-25,29,5.
