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浆膜腔积液转移性肺腺癌细胞中 TTF-1及 NapsinA 的表达

余清 苏亚婷 李慧

医学信息2016,Vol.29Issue(17):41-42,2.
医学信息2016,Vol.29Issue(17):41-42,2.

浆膜腔积液转移性肺腺癌细胞中 TTF-1及 NapsinA 的表达

Expression of TTF-1 and NapsinA on Metastatic Pulmonary Adenocarcinoma Cells in Serous Effusions

余清 1苏亚婷 1李慧1

作者信息

  • 1. 德阳市人民医院病理科,四川 德阳 618000
  • 折叠

摘要

Abstract

Objective To analyze the expression of TTF -1 and NapsinA in the metastatic pulmonary adenocarcinoma cells in serous effusions. Methods A total of 112 cases of effusion cytology were evaluated.The primary sites of origin were confirmed clinically or histologically in all patients. There were 86 adenocarcinomas from the lung,5 squamous carcinoma from lung,2 small cell carcinoma from lung,13 adenocarcinomas from stomach and 1 adenocarcinomas from pancreas.HE and cell block were prepared for each case.Immunocytochemical study were performed on the cell block sections. Results TTF-1 expressed in 73 lung adenocarcinomas and the sensitivity was 84.9%,specificity was 96.2%,NapsinA expressed in 76 lung adenocarcinomas and the sensitivity was 88.4% ,specificity was 100% . Conclusion NapsinA is a higher sensitive and specific marker for adenocarcinomas of the lung in the serous effusions.

关键词

甲状腺转录因子-1/天门冬氨酸蛋白酶/肺腺癌/浆膜腔积液/细胞块/免疫细胞化学

Key words

Thyroid transcription factor -1/Noval aspartic proteinase of the pepsin family A/Lung adenocarcinoma/Serous effusion/Cell block/Immunocytochemistry

引用本文复制引用

余清,苏亚婷,李慧..浆膜腔积液转移性肺腺癌细胞中 TTF-1及 NapsinA 的表达[J].医学信息,2016,29(17):41-42,2.

医学信息

1006-1959

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