摘要
Abstract
Objective To study the relationship between obstructive sleep apnea syndrome (OSAS)and hypothyroidism ,to evaluate the prevalence of hypothyroidism. To confirm the feasibility study about thyroid function testing in OSAS is checked. Methods A retrospective analysis of cases of sleep apnea and with hypothyroidism and review of the literature. 60 patients with proven OSAS (apnea index [AHl]>15) and thyroid function testing. Results 1 Hypothyroidism has been shown to be frequently related with OSAS and many clinically apparent similariti. the prevalence of hypothyroidism was no significant difference,pothyroidism prevalence rate of all groups of patients with OSAS, with age, the incidence rate increased. OSAS patients, 2.0% prevalence of hypothyroidism, hypothyroidism, the prevalence of OSAS in patients up to 52% or more. 2. This study of 60 cases of hospitalized patients with moderate to severe OSAS were found in 5 cases of hypothyroidism, accounting for 8.3%, 10% female patients, over 50 years the incidence rate of 20%. 2 patients had typical clinical symptoms of hypothyroidism, in six months to one year significantly increased apnea. 3 patients without typical symptoms of hypothyroidism, including 1 with pituitary tumor, active acromegaly, and 1 with metabolic syndrome and subclinical hypothyroidism, and 1 case of only daytime sleepiness, nocturnal snoring, apnea. Hypothyroidism and / or ventilator treatment, hypothyroidism, sleep apnea symptoms and reduced. 3.5 cases of patients 3 months after discharge follow-up results: adhere to the ventilation in the treatment in 4 cases, the disease improved, OSAS was significantly reduced, while receiving both treatments in 2 cases, the condition improved thyroid function in the recovery. Only 1 case of thyroid hormone replacement therapy, the disease no obvious improvement.Conclusion OSAS and hypothyroidism are relatively common disorders that have similar clinical features and are thought to be causally linked.epidemiological and interventional studies suggest that OSAS increases the cardiovascular risk and that its treatment may reduce this risk,the therapy such as continuous positive airway pressure is recommended . OSAS from hypothyroidism can disappear after replace treatment with , Existing information, OSAS patients and the general population suffering from the incidence of hypothyroidism was no significant difference. Epidemiology and the relationship between the two is not very clear for all OSAS patients without the need for screening of thyroid function. But there are clinical manifestations of OSAS patients with hypothyroidism and women over 50 years and moderate to severe OSAS patients should be screened for hypothyroidism, especially the recent significant serever in patients with sleep apnea. Clinical experience in patients with moderate to severe OSAS do not ignore the existence of clinical manifestations of hypothyroidism. In addition, all existing hypothyroidism should consider the possibility of OSAS, in particular the emergence of snoring, daytime sleepiness and other symptoms. Relevant medical personnel to understand the basics of OSAS and hypothyroidism, clinical testing technology and related treatment to reduce misdiagnosis of hypothyroidism. We sought to determine the prevalence of previously unrecognized hypothyroidism in a series of patients evaluated for OSAS and whether an association between hypothyroidism and OSAS was present. ① thyroid function studies need not be done routinely for every OSAS patient;② an overnight sleep study is necessary in every case of hypothyroidism.关键词
睡眠呼吸暂停综合征/甲状腺功能减退症/甲功实验/可行性Key words
Sleep apnea syndrome/Hypothyroidism(thyroid function testing)/Continuous positive airway pressure
