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自噬研究的新动向-自噬流

马培泽 孙正新 姜月华

医学信息2016,Vol.29Issue(19):28-29,2.
医学信息2016,Vol.29Issue(19):28-29,2.

自噬研究的新动向-自噬流

New Trends in Autophagy Research-Autophagy Flow

马培泽 1孙正新 2姜月华3

作者信息

  • 1. 威海市中医院,山东 威海 264200
  • 2. 威海市环翠区妇幼保健院,山东 威海 264200
  • 3. 山东中医药大学附属医院,山东 济南 250011
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摘要

Abstract

Autophagy is one of the hot topics in biomedical research.Which is widely involved in various physiological and pathological processes. Previous studies on autophagy have evaluated the level of autophagosome,and recently found that the increase of autophagosome can not reflect the level of autophagy in nature.It can only reflect the induction of autophagy and the inhibition of autophagosome.From the point of autophagy flux,the number of the autophagosome is affected by the formation and removal of the two aspects,accurate and comprehensive assessment of autophagy not only includes the detection of the body,but also includes the dynamic observation of the entire flux ofautophagy is smooth.We promote the combination of dynamic and static detection methods to obtain reliable data,which can effectively explain the occurrence of autophagy and the changes of autophagy flux.

关键词

自噬/自噬流/透射电子显微镜

Key words

Autophagy/autophagy flux/Transmission electron microscope

引用本文复制引用

马培泽,孙正新,姜月华..自噬研究的新动向-自噬流[J].医学信息,2016,29(19):28-29,2.

基金项目

山东省自然科学基金 ()

医学信息

1006-1959

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