中国感染控制杂志2016，Vol.15Issue(7)：452-456,5.DOI:10.3969/j.issn.1671-9638.2016.07.003
耐替加环素鲍曼不动杆菌的同源性及临床分布
Homology and clinical distribution of tigecycline-resistant Acinetobacter baumannii
摘要
Abstract
Objective To study the homology and clinical distribution of tigecycline-resistant Acinetobacter baumannii (A.baumannii )in a hospital.Methods Multidrug-resistant A.baumannii (MDRAB,n = 88 )from specimens from clinical departments of a hospital in 2013-2014 were collected and detected susceptibility to tigecy-cline;homology of tigecycline-resistant strains were detected by pulsed-field gel electrophoresis (PFGE),clinical characteristics and distribution of infected patients were analyzed.Results 88 patients didn’t use tigecycline before MDRAB were isolated.Of 88 MDRAB strains,4 (4.55%)were resistant to tigecycline,which were No.10,31 , 33,and 87 strains.PFGE results revealed that No.31 ,33,and 87 strains were of the same genotype,and with high homology,which distributed in three different departments;No.31 strain was detected from general intensive care unit (ICU),No.33 strain was detected from emergency ICU,although strains were detected from different depart-ments,patients were transferred before strains were isolated,and were admitted to departments of gastrointestinal surgery and emergency ICU during the same period;No.87 strain was detected from neurosurgical ICU and patient had never been transferred,the detection time was 7-8 months later than No.31 and 33 strains.No.10 strain was isolated from emergency ICU,patient was not transferred.Conclusion Of MDRAB isolated in this hospital,tigecy-cline-resistant strains are low,most strains are homologous,cross infection may be exists in different departments.关键词
鲍曼不动杆菌/替加环素耐药/传播/同源性/临床分析Key words
Acinetobacter baumannii/tigecycline resistance/transmission/homology/clinical analysis分类
医药卫生引用本文复制引用
刘延媛,张瑞凌,刘汉冕,曹海燕,周仕丹,张扣兴..耐替加环素鲍曼不动杆菌的同源性及临床分布[J].中国感染控制杂志,2016,15(7):452-456,5.基金项目
广东省惠州市科技局基金资助项目 （）
