中国感染控制杂志2016，Vol.15Issue(7)：471-475,5.DOI:10.3969/j.issn.1671-9638.2016.07.007
某医院感染病区2011-2015年临床分离病原菌及其耐药性
Distribution and antimicrobial resistance of clinically isolated bacteria from department of infectious diseases of a hospital in 2011-2015
摘要
Abstract
Objective To understand the distribution and antimicrobial resistance of pathogenic bacteria isolated from patients in the department of infectious diseases in Xiangya Hospital.Methods The distribution and antimicrobial susceptibility testing results of pathogenic bacteria isolated from patients in this department in 2011 -2015 were analyzed retrospectively.Results A total of 560 strains were isolated during 5 years,of which gram-posi-tive bacteria and gram-negative bacteria accounted for 44.1 % (n =247)and 55.9%(n =313)respectively.69.8%(81/116)of coagulase-negative staphylococcus and 24.3%(9/37)of Staphylococcus aureus were methicillin-resistant (MRCNS,MRSA)respectively.Enterococcus was highly susceptible to vancomycin,linezolid,and phosphonomy-cin (>81 %).Enterobacteriaceae remained highly susceptible to carbapenems (88.9%-100.0%),and was suscep-tible to amikacin,cefoperazone/sulbactam,and piperacillin/tazobactam (>84%).Acinetobacter baumannii was the major isolated multidrug-resistant organism (MDRO),isolation rate of imipenem-resistant Acinetobacter baumannii increased from 50.0% in 2011 to 77.8% in 2015,its resistance rate to imipenem was 64.9%.Conclusion The majority of clinically isolated pathogenic bacteria from this department is gram-negative bacilli,and detection rate of MDROs showed an upward trend;antimicrobial agents should be chosen according to distribution and antimicrobial resistance of pathogenic bacteria.关键词
感染病区/病原菌/抗菌药物/抗药性,微生物/耐药性/合理用药Key words
department of infectious diseases/pathogenic bacteria/antimicrobial agent/drug resistance,microbi-al/drug resistance/rational drug use分类
医药卫生引用本文复制引用
李军,刘清霞,黄泽炳,黄燕,周蓉蓉..某医院感染病区2011-2015年临床分离病原菌及其耐药性[J].中国感染控制杂志,2016,15(7):471-475,5.基金项目
湖南省发改委 （）
