中国康复理论与实践2016，Vol.22Issue(7)：779-783,5.DOI:10.3969/j.issn.1006-9771.2016.07.008
腓肠肌外侧头肌支神经转移术对大鼠腓深神经损伤的修复作用
Effects of Lateral Gastrocnemius Muscle Branch Nerve Transferring on Deep Peroneal Nerve Impairment in Rats
摘要
Abstract
Objective To explore the feasibility and effectiveness of lateral gastrocnemius muscle branch nerve transferring for deep pe-roneal nerve injury. Methods Thirty-two adult female Sprague-Dawley rats were divided into control group (n=8), sham group (n=8), nerve direct repairing group (n=8) and nerve transferring group (n=8). Twelve weeks after the anastomosis, the nerve anastomosis was observed vi-sually, the length of lateral of gastrocnemius muscle branch (L1), the diameter at the point of entering muscle (D1), the maximum detachable length of nervus peroneus communis (L2), the diameter of deep peroneal nerve (D2) and the distance between branch point and neck of fibu-la (S) were measured. The peroneal nerve functional index (PFI), the amplitude of compound muscle action potential (CMAP), nerve con-duction velocity (NCV), the weight of the tibialis anterior and the creatine kinase (CK) activity of theanterior tibial were compared among groups. Results L1<S was found in all the rats, indicating that the proximal tibial nerve muscular branches could not directly anastomose with the deep peroneal nerve in the neck of fibula without tension. The PFI, amplitude of CAMP, NCV, weight of the tibialis anterior and CK activity all improved in the nerve transferring group compared with those in the control group (P<0.05), and were not different from the nerve direct repairing group (P>0.05). Conclusion It is feasible that lateral head muscular branches of gastrocnemius nerve transferring can repair deep peroneal nerve injury, which is needed to separate superficial peroneal nerve and deep peroneal nerve in the epineurium without damaging nerve for tension free neuroanastomosis. Lateral head muscular branches of gastrocnemius nerve transferring can repair the func-tion after deep peroneal nerve injury.关键词
腓深神经损伤/胫神经肌支/神经转移术/修复/大鼠Key words
deep peroneal nerve injury/tibial nerve muscular branches/nerve transfer/repair/rats分类
医药卫生引用本文复制引用
李军,王冲,李建军,刘长彬,董学超,郭韵,唐丽,杜良杰,高峰,刘宏炜,杨德刚..腓肠肌外侧头肌支神经转移术对大鼠腓深神经损伤的修复作用[J].中国康复理论与实践,2016,22(7):779-783,5.基金项目
中央级公益性科研院所基本科研业务费专项资金重点支持课题(No.2013CZ-1)。 （No.2013CZ-1）
