中国康复理论与实践2016，Vol.22Issue(7)：844-847,4.DOI:10.3969/j.issn.1006-9771.2016.07.025
颈脊髓损伤患者肺部感染的病原菌特点及抗生素应用
Pathogen of Pulmonary Infection in Patients with Cervical Spinal Cord Injury and Antibiotics Therapy
赵国伟 1高钧1
作者信息
- 1. 中国康复研究中心北京博爱医院药剂科，北京市100068
- 折叠
摘要
Abstract
Objective To investigate the distribution and drug resistance of pathogen for pulmonary infection in cervical spinal cord inju-ry (CSCI) patients, and analyze the application of antibiotics. Methods From January, 2014 to June, 2015, 156 patients with CSCI were re-viewed. The bacteriology and drug resistance were investigated, as well as the application of antibiotics. Results There were 45 cases with nosocomial infection of 68 times, and 106 strains of bacteria in total. The top four Gram-negative pathogens were Klebsiella pneumonia (17.9%), Pseudomonas aeruginosae (15.1%), Encherichia coli (11.3%) and Acinetobacter baumannii (8.5%). The main Gram-positive cocci was Staphylococcus aureus (9.4%), and the main fungi was Candida tropicalis (0.7%). Gram-negative bacteria was resistant to the second or third generation cephalosporins and quinolones moderately or severely, but sensitive toβ-lactamase inhibitor combinations and aminoglyco-sides. The main Gram-positive cocci were sensitive to vancomycin. The application of antibiotics needed to be improved. Conclusion The Gram-negative bacteria are the chief pathogen for pulmonary infection in CSCI patients, which show multiple drug-resistant. It is significant to monitor the drug resistance of bacteria and optimize antibiotics.关键词
颈脊髓损伤/肺部感染/病原菌/耐药/抗生素Key words
cervical spinal cord injury/pulmonary infection/pathogens/drug-resistant/antibiotics分类
医药卫生引用本文复制引用
赵国伟,高钧..颈脊髓损伤患者肺部感染的病原菌特点及抗生素应用[J].中国康复理论与实践,2016,22(7):844-847,4.
