中国临床药理学杂志2016，Vol.32Issue(13)：1192-1193,1213,3.DOI:10.13699/j.cnki.1001-6821.2016.13.012
呼吸道铜绿假单胞菌体外药敏试验研究
Study on the drug sensitivity test of respiratory Pseudomonas aeruginosa in vitro
摘要
Abstract
Objective To analyze the drug sensitivity of respiratory Pseudomonas aeruginosa.Methods Drug sensitivity test of 481 isolated strains of Pseudomonas aeruginosa was performed with agar dilution method in vitro. The susceptibility , drug resistance and intermediary rate of strains of Pseudomonas aeruginosa and those insensitive to imipenem were determined according to the minimal inhibitory concentration ( MIC ) . Results Pseudomonas aeruginosa in respiratory had the lowest resistance rate to amikacin (12.06%), followed by imipenem with 13.93%resis-tance and had the highest resistance to sulfamethoxazole /trimethoprim ( SMZ/TMP) which was 99.79%.96 strains insensitive to imipenem had the lowest resistance to amikacin ( 16.67%) , but to SMZ/TMP they had highest resistance rate of 98.96%.Conclusion According to drug re-sistance status of Pseudomonas aeruginosa bacteria in our hospital , the empirical treatment with imipenem , ciprofloxacin and other antimicrobial agents was recommended , and based on this , the combined use of amika-cin is expected to achieve better control effect .关键词
呼吸道/铜绿假单胞菌/体外药敏试验/耐药性Key words
respiratory tract/Pseudomonas aeruginosa/drug sensitivity test/drug resistance分类
医药卫生引用本文复制引用
张小华,杨祚明,范长玲,黎美凤..呼吸道铜绿假单胞菌体外药敏试验研究[J].中国临床药理学杂志,2016,32(13):1192-1193,1213,3.基金项目
海南省卫生厅科学研究基金资助项目 （）
