中国临床药理学杂志2016，Vol.32Issue(14)：1299-1303,5.DOI:10.13699/j.cnki.1001-6821.2016.14.015
导尿管相关菌尿的病例特点及病原学耐药分析
Bacterial resistant pattern and clinical characteristics in cases of catheter related bacteriuria
李湘燕 1杨阳 1王玉芳1
作者信息
- 1. 北京大学 第一医院 临床药理研究所，北京100034
- 折叠
摘要
Abstract
Objective To summarize bacterial resistance and clinical characteristics in the cases of catheter related bacteriuria .Methods A total of 1831 cases of catheter related bacteriuria and non -catheter relat-ed bacteriuria from January 2010 to December 2014 were included.The general characteristics were reviewed in electronic medical records .Mini-mal inhibitory concentration ( MIC) test were used to detect the antimi-crobial sensitivity of bacteria .Results There was 55.9% and 57.2%of cases appeared as asymptomatic bacteriuria in catheter related cases and non-catheter related cases , all the cases received antibiotic therapy during hospitalization .There was no difference in clinical outcome be-tween the group of asymptomatic bacteriuria and urinary tract infection in catheter related bacteria.Escherichia coli occupied the first place in the isolation of pathogen from both catheter related ( 35.2%) and non -catheter related ( 60.1%) cases.The resistant rate of Escherichia coli from catheter related/non -catheter related sample to cephalosporins , piperacillin/tazobactam , quinolones and nitrofurantoin was 65%-80%/29.4% -68.8%, 4.9% -9.8%/2.9% -4.2%, 85% -90%/62.7%-77.3%and 0-16.7%/7.4%-8.3%, respectively.No resistant strain to linezolid was found in Enteroco-ccus.The resistant rate of Pseudomonas aeruginosa from urine catheter/non -catheter related sample to ceftazidim , piperacillin/tazobactam, carbapenems was 11.9% -16.1%/5.9% -7.5%,4.8% -12.5%/2.9% -10.0% and 11.9%-37.8%/2.5%-8.6%, respectively.The resistant rates of Pseudomonas aeruginosa in the group of infection were lower than those in the group of asymptomatic bacteriuria . Conclusion The patients with asymptomatic bacteriuria were received unnecessary antibiotic therapy .The resistant rates of bacteria from catheter were higher than those from non-catheter sample.关键词
导尿管/尿路感染/无症状菌尿/细菌耐药Key words
urine catheter/urinary tract infection/asymptomatic bacteriuria/bacterial resistance分类
医药卫生引用本文复制引用
李湘燕,杨阳,王玉芳..导尿管相关菌尿的病例特点及病原学耐药分析[J].中国临床药理学杂志,2016,32(14):1299-1303,5.
