中国免疫学杂志2016,Vol.32Issue(7):1050-1052,3.DOI:10.3969/j.issn.1000-484X.2016.07.026
慢性荨麻疹患者幽门螺杆菌检测的意义
Significance of HP detection in patients of chronic urticaria
王春苗 1吴慰师 2朱锦宏 3周茂华 1王蔚莎1
作者信息
- 1. 广东省人民医院/广东省医学科学院病理医学部检验科,广州 510080
- 2. 广东省人民医院/广东省医学科学院皮肤科,广州 510080
- 3. 广州医科大学附属第二医院检验科,广州 510260
- 折叠
摘要
Abstract
Objective:To study the correlation between chronic urticaria and Helicobacter pylori infection,and to explore the significance of HP detection in the diagnosis and treatment of chronic urticaria. Methods: Totally 420 cases of chronic urticaria,who were treated in outpatient department from April 2014 to July 2015,and 450 cases of healthy physical people were selected randomly as healthy control group in the same period,then the serum HP unease antibody was detected by colloidal gold method,the positive rate of two groups patients with HP was analysed. Meanwhile 162 chronic urticaria patients with positive HP were divided into experimental group with 88 cases and control group with 74 cases. The patients in the control group were treated with conventional treatment,while the experimental group were treated with triple therapy based on the treatment of control group,and the clinical efficacy of different ther-apeutic methods was analysed in the chronic urticaria patients with positive HP. Results: The positive rate of HP in chronic urticaria group was 38. 6%, and the positive rate of HP in healthy control group was 14. 4%, the difference was statistically significant ( P<0. 05). The effective rate of clinical efficacy in the experimental group was significantly higher than the control group(P<0. 05). Con-clusion:There is close correlation between chronic urticaria and HP infection,HP detection has important clinical significance for the diagnosis and treatment of chronic urticaria.关键词
慢性荨麻疹/幽门螺杆菌/胶体金法Key words
Chronic urticaria/Helicobacter pylori/Colloidal gold method分类
医药卫生引用本文复制引用
王春苗,吴慰师,朱锦宏,周茂华,王蔚莎..慢性荨麻疹患者幽门螺杆菌检测的意义[J].中国免疫学杂志,2016,32(7):1050-1052,3.