中国普通外科杂志2016，Vol.25Issue(7)：957-964,8.DOI:10.3978/j.issn.1005-6947.2016.07.005
前入路与传统入路右半肝切除术治疗肝癌疗效的Meta分析
Anterior approach versus conventional approach in right hemihepatectomy for liver cancer：a Meta-analysis
摘要
Abstract
Objective: To compare the clinical efficacy of anterior approach and conventional approach in right hemihepatectomy for hepatocellular carcinoma. <br> Methods: Literature on studies comparing anterior approach and conventional approach for right hemihepatectomy in treatment of hepatocellular carcinoma was obtained through computerized and manual searches. hTe quality of the included studies was assessed, according to the Cochrane guidelines, and atfer data extraction, the Meta-analysis was performed by RevMan 5.3 sotfware. <br> Results: Nine studies were finally included, involving 1 344 patients, of whom 619 cases received anterior approach operation and 725 cases underwent conventional approach operation. The results of Meta-analysis showed that patients undergoing anterior approach operation were superior to those undergoing conventional approach operation in 1, 3-year overall survival (OR=1.85, 95%CI=1.25–2.71,P=0.002;OR=3.11, 95%CI=2.16–4.46,P<0.00001) and disease free survival (OR=2.27, 95%CI=1.60–3.22,P<0.00001;OR=3.13, 95%CI=2.11–4.64,P<0.00001) as well as perioperative mortality (OR=0.33, 95%CI=0.15–0.70,P=0.004); there was no statistical difference in operative time, intraoperative blood loss, incidence of postoperative complications and length of hospital stay between patients undergoing anterior approach operation and conventional approach operation (allP>0.05). <br> Conclusion: Anterior approach right hemihepatectomy is safe and better in meeting the tumor-free principle than conventional approach, and it can also improve the overall survival rate, disease-free survival rate and reduce perioperative mortality.关键词
肝肿瘤/肝切除术/Meta分析Key words
Liver Neoplasms/Hepatectomy/Meta-analysis分类
医药卫生引用本文复制引用
佟庆,晏冬,毛拉艾沙·买买提,唐津天,尹继炜,丁伟..前入路与传统入路右半肝切除术治疗肝癌疗效的Meta分析[J].中国普通外科杂志,2016,25(7):957-964,8.基金项目
新疆医科大学科研创新基金资助项目（XYDCX2014100）。 （）
