中国社区医师2016，Vol.32Issue(21)：14-14,16,2.DOI:10.3969/j.issn.1007-614x.2016.21.5
基于人群研究药代动力学/药效学和蒙特卡罗模拟加雷沙星最佳剂量
Study on population pharmacokinetics/pharmacodynamics and Monte Carlo simulation garenoxacin optimal dose
摘要
Abstract
Objective:To explore the population pharmacokinetic/pharmacodynamics and Monte Carlo simulation garenoxacin optimal dose.Methods:The patients were given garenoxacin 400 mg,1 time one day,for 10 days,the clinical curative effect was evaluated.Results:92.4%(61/66) achieved the target value of fAUC0-24/MIC ratio more 30 hours,the clinical effective rate was 91.8% (56/61).Conclusion:For the patients with respiratory tract infection,the garenoxacin ideal dose is 400 mg for 1 time one day.关键词
药代动力学/药效学/加雷沙星/最佳剂量Key words
Pharmacokinetics/Pharmacodynamics/Garenoxacin/Optimal dose引用本文复制引用
赵勇刚..基于人群研究药代动力学/药效学和蒙特卡罗模拟加雷沙星最佳剂量[J].中国社区医师,2016,32(21):14-14,16,2.
